EKSTRAKSI SENYAWA BIOAKTIF THEAFLAVIN TEH OOLONG (CAMELLIA SINESIS) DENGAN AIR SEBAGAI GREEN SOLVENT

Theaflavin, a polyphenolic compounds found  in oolong tea and black tea, thought to have medicinal potency. Theaflavins and their derivatives such as theaflavin gallate have shown a broad spectrum of antiviral activity against several viruses, including influenza A, B and hepatitis C viruses. Previo...

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Main Authors: Amalia, Rizka (Author), Yulianto, Mohamad Endy (Author), Purwantisari, Susiana (Author), Yudanto, Yusuf Arya (Author), Pangestu, Ilyas Teguh (Author)
Format: EJournal Article
Published: Vocational School Diponegoro University, 2020-10-30.
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LEADER 02348 am a22002893u 4500
001 GT_UNDIP_32287_18209
042 |a dc 
100 1 0 |a Amalia, Rizka  |e author 
700 1 0 |a Yulianto, Mohamad Endy  |e author 
700 1 0 |a Purwantisari, Susiana  |e author 
700 1 0 |a Yudanto, Yusuf Arya  |e author 
700 1 0 |a Pangestu, Ilyas Teguh  |e author 
245 0 0 |a EKSTRAKSI SENYAWA BIOAKTIF THEAFLAVIN TEH OOLONG (CAMELLIA SINESIS) DENGAN AIR SEBAGAI GREEN SOLVENT 
260 |b Vocational School Diponegoro University,   |c 2020-10-30. 
500 |a https://ejournal.undip.ac.id/index.php/gema_teknologi/article/view/32287 
520 |a Theaflavin, a polyphenolic compounds found  in oolong tea and black tea, thought to have medicinal potency. Theaflavins and their derivatives such as theaflavin gallate have shown a broad spectrum of antiviral activity against several viruses, including influenza A, B and hepatitis C viruses. Previous research show that theaflavins could inhibit RdRp activity through blocking the active site in the catalytic pocket of RdRp in SARS‐CoV‐2, SARS‐CoV and MERS‐CoV.. This research aims to extract theaflavins in oolong tea with water solvent at a temperature of 100oC, pressure > 1 atm and varied extraction times (10-60 minutes). The effect of oolong tea extraction time towards the  theaflavin content was observed. The results showed that with the longer extraction time, the theaflavin levels were reduced due to the degradation of thermal theaflavins into thearubigins. The model exponential equation obtained is  y=14,91488 e-0,2631x + 0,11865, with the R2=0.99161. The best operating conditions was obtained at 10 minutes of extraction time, resulted in 1.19% of the total theaflavin content of oolong tea. 
540 |a Copyright (c) 2020 Gema Teknologi 
546 |a eng 
690 |a teh oolong; theaflavin; ekstraksi; green solvent; SARS-CoV-2 
655 7 |a info:eu-repo/semantics/article  |2 local 
655 7 |a info:eu-repo/semantics/publishedVersion  |2 local 
655 7 |2 local 
786 0 |n Gema Teknologi; Vol 21, No 1 (2020): April 2020 - October 2020; 16 - 20 
786 0 |n 2656-582X 
786 0 |n 0852-0232 
787 0 |n https://ejournal.undip.ac.id/index.php/gema_teknologi/article/view/32287/18209 
856 4 1 |u https://ejournal.undip.ac.id/index.php/gema_teknologi/article/view/32287/18209  |z Get Fulltext