Optimization Extraction of Xylocarpus granatum Stem as Antioxidant and Antiglycation

Xylocarpus granatum is an Indonesian plant that has bioactives content of phenols and high antioxidant activity on it. The aim of this research was to determine the optimum condition maceration for Xylocarpus granatum stem as antioxidant and antiglycation. The optimum conditions of maceration were e...

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Main Authors: Sapitri, Eka Winarni (Author), Batubara, Irmanida (Author), Syafitri, Utami Dyah (Author)
Format: EJournal Article
Published: Bogor Agricultural University, Indonesia, 2019-10-27.
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LEADER 02291 am a22002893u 4500
001 HAYATI_27973_pdf
042 |a dc 
100 1 0 |a Sapitri, Eka Winarni  |e author 
700 1 0 |a Batubara, Irmanida  |e author 
700 1 0 |a Syafitri, Utami Dyah  |e author 
245 0 0 |a Optimization Extraction of Xylocarpus granatum Stem as Antioxidant and Antiglycation 
260 |b Bogor Agricultural University, Indonesia,   |c 2019-10-27. 
500 |a https://journal.ipb.ac.id/index.php/hayati/article/view/27973 
520 |a Xylocarpus granatum is an Indonesian plant that has bioactives content of phenols and high antioxidant activity on it. The aim of this research was to determine the optimum condition maceration for Xylocarpus granatum stem as antioxidant and antiglycation. The optimum conditions of maceration were effected by the extraction variables (concentration, sample/solvent ratio, extraction time) were evaluated using surface response method. The optimum condition was determined from the recovery of the respons. The optimum condition of maceration is predicted to be achieved when the solvent concentration is 52.25%, the extraction time is 15.92 hours, sample/solvent ratio is 1 g/9 ml with the response (yield, total phenol content, flavonoid, inhibition for 2,2'-diphenylpicryl hydrazyl, capacity of 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), and inhibition antiglycation were 12.81%, 1.95 mg of gallic acid/g extract, 62.33 μg quercetin/g extract, 41.11%, 0.71 TEAC, and 112.33%, respectively). Optimization extraction conditions shows that the extraction variables have significant effect on respons so it can reduce the extraction time, economic, and produce high bioactivite constituens. 
546 |a eng 
690 |a ABTS 
690 |a antiglycation 
690 |a DPPH 
690 |a stem of Xylocarous granatum 
655 7 |a info:eu-repo/semantics/article  |2 local 
655 7 |a info:eu-repo/semantics/publishedVersion  |2 local 
655 7 |a Peer-reviewed Article  |2 local 
786 0 |n HAYATI Journal of Biosciences; Vol. 26 No. 2 (2019): April 2019; 50 
786 0 |n 2086-4094 
786 0 |n 1978-3019 
787 0 |n https://journal.ipb.ac.id/index.php/hayati/article/view/27973/pdf 
856 4 1 |u https://journal.ipb.ac.id/index.php/hayati/article/view/27973/pdf  |z Get fulltext