Comparison Between the Potential of Tempe Flour Made from Germinated and Nongerminated Soybeans in Preventing Diabetes Mellitus

This study was aimed to compare the chemical characteristics of tempe flour made from nongerminated soybean (NST) and germinated soybean (GST), especially on their capacity in preventing diabetes mellitus (DM). Soybeans were germinated for 20 hours in the dark until 2.5-5.0 mm of the radicle emerged...

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Main Authors: Astawan, Made (Author), Rahmawati, Inas Suci (Author), Cahyani, Ananda Putri (Author), Wresdiyati, Tutik (Author), Putri, Sastia Prama (Author), Fukusaki, Eiichiro (Author)
Format: EJournal Article
Published: Bogor Agricultural University, Indonesia, 2020-01-01.
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LEADER 02454 am a22002773u 4500
001 HAYATI_30306_19545
042 |a dc 
100 1 0 |a Astawan, Made   |e author 
700 1 0 |a Rahmawati, Inas Suci   |e author 
700 1 0 |a Cahyani, Ananda Putri   |e author 
700 1 0 |a Wresdiyati, Tutik   |e author 
700 1 0 |a Putri, Sastia Prama   |e author 
700 1 0 |a Fukusaki, Eiichiro   |e author 
245 0 0 |a Comparison Between the Potential of Tempe Flour Made from Germinated and Nongerminated Soybeans in Preventing Diabetes Mellitus 
260 |b Bogor Agricultural University, Indonesia,   |c 2020-01-01. 
500 |a https://journal.ipb.ac.id/index.php/hayati/article/view/30306 
520 |a This study was aimed to compare the chemical characteristics of tempe flour made from nongerminated soybean (NST) and germinated soybean (GST), especially on their capacity in preventing diabetes mellitus (DM). Soybeans were germinated for 20 hours in the dark until 2.5-5.0 mm of the radicle emerged. The ungerminated soybeans and the germinated soybeans were then processed into tempe and tempe flour. The two types of tempe flour were subjected to proximate analysis, amino acid profiling, antioxidant capacity, total phenol content, isoflavone content, and α-amylase and α-glucosidase enzyme inhibition analyses. GST was superior in preventing DM in the protein content and antioxidant parameters, as these were significantly higher (p<0.05) than in NST. On the other hand, NST was superior in preventing diabetes in the isoflavon (daidzein, genistein, and total isoflavone) and α-amylase inhibition IC50 parameters which were significantly better (p<0.05) than in GST. On the contrary, the diabetes-preventing parameters total phenols, α-glucosidase inhibition IC50, and insulinotropic amino acids (arginine, alanine, phenilalanine, isoleucine, leucine, and lysine) were not different (p>0.05).  Therefore, GST and NST both have potential in preventing diabetes through different mechanisms. 
546 |a eng 
655 7 |a info:eu-repo/semantics/article  |2 local 
655 7 |a info:eu-repo/semantics/publishedVersion  |2 local 
655 7 |a Peer-reviewed Article  |2 local 
786 0 |n HAYATI Journal of Biosciences; Vol. 27 No. 1 (2020): January 2020; 16 
786 0 |n 2086-4094 
786 0 |n 1978-3019 
787 0 |n https://journal.ipb.ac.id/index.php/hayati/article/view/30306/19545 
856 4 1 |u https://journal.ipb.ac.id/index.php/hayati/article/view/30306/19545  |z Get fulltext