Propolis Components and Biological Activities from Stingless Bees Collected on South Sulawesi, Indonesia
Three new compounds, namely sulabiroins A (1) and B (2), and 2',3'-dihydro-3'-hydroxypapuanic acid (3), were isolated from the propolis of stingless bees (Tetragonula aff. biroi) collected on South Sulawesi, Indonesia. In addition, ten known compounds, (-)-papuanic acid (4), (-)-isoca...
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| Main Authors: | , , , , , |
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| Format: | EJournal Article |
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Bogor Agricultural University, Indonesia,
2020-01-01.
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| LEADER | 02286 am a22002773u 4500 | ||
|---|---|---|---|
| 001 | HAYATI_30313_19552 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Miyata, Ryo |e author |
| 700 | 1 | 0 | |a Sahlan, Muhamad |e author |
| 700 | 1 | 0 | |a Ishikawa, Yoshinobu |e author |
| 700 | 1 | 0 | |a Hashimoto, Hiroshi |e author |
| 700 | 1 | 0 | |a Honda, Sari |e author |
| 700 | 1 | 0 | |a Kumazawa, Shigenori |e author |
| 245 | 0 | 0 | |a Propolis Components and Biological Activities from Stingless Bees Collected on South Sulawesi, Indonesia |
| 260 | |b Bogor Agricultural University, Indonesia, |c 2020-01-01. | ||
| 500 | |a https://journal.ipb.ac.id/index.php/hayati/article/view/30313 | ||
| 520 | |a Three new compounds, namely sulabiroins A (1) and B (2), and 2',3'-dihydro-3'-hydroxypapuanic acid (3), were isolated from the propolis of stingless bees (Tetragonula aff. biroi) collected on South Sulawesi, Indonesia. In addition, ten known compounds, (-)-papuanic acid (4), (-)-isocalolongic acid (5), isopapuanic acid (6), isocalopolyanic acid (7), glyasperin A (8), broussoflavonol F (9), (2S)-5,7-dihydroxy-4'-methoxy-8-prenylflavanone (10), isorhamnetin (11), (1'S)-2-trans,4-trans-abscisic acid (12), and (1'S)-2-cis,4-trans-abscisic acid (13) were identified. The structures of the new and known compounds were determined by spectroscopic analysis. The absolute configurations of sulabiroins A (1) and B (2) were determined by X-ray crystallography analysis and ECD calculation, respectively. The propolis from stingless bee (Tetragonula aff. biroi) collected on South Sulawesi contained compounds not present in propolis from other regions. Sulabiroin A (1) and isorhamnetin (11) were examined for xanthine oxidase (XO) inhibitory activity as one of biological activities; isorhamnetin (11) exhibited potent XO inhibitory activity, with an IC50 value of 3.9 µm. | ||
| 546 | |a eng | ||
| 655 | 7 | |a info:eu-repo/semantics/article |2 local | |
| 655 | 7 | |a info:eu-repo/semantics/publishedVersion |2 local | |
| 655 | 7 | |a Peer-reviewed Article |2 local | |
| 786 | 0 | |n HAYATI Journal of Biosciences; Vol. 27 No. 1 (2020): January 2020; 82 | |
| 786 | 0 | |n 2086-4094 | |
| 786 | 0 | |n 1978-3019 | |
| 787 | 0 | |n https://journal.ipb.ac.id/index.php/hayati/article/view/30313/19552 | |
| 856 | 4 | 1 | |u https://journal.ipb.ac.id/index.php/hayati/article/view/30313/19552 |z Get fulltext |