Association of GHR|AluI gene polymorphism with body weight parameters in Grati-PO cattle
The growth hormone receptor (GHR) gene is member of the class I cytokine receptor family that important in growth regulation including in cattle. This study aimed to analyze the association between GHR|AluI gene with body weight, parameters in Grati-PO cattle population. A total of 304 blood samples...
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| Main Authors: | , , , , , , |
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| Format: | EJournal Article |
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Diponegoro University,
2021-12-02.
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| LEADER | 02593 am a22003133u 4500 | ||
|---|---|---|---|
| 001 | JITAA_UNDIP_36665_pdf | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Hartati, H. |e author |
| 700 | 1 | 0 | |a Hapsari, A.A.R. |e author |
| 700 | 1 | 0 | |a Soewandi, B. D. P. |e author |
| 700 | 1 | 0 | |a Anwar, S. |e author |
| 700 | 1 | 0 | |a Rahmadani, S. P. |e author |
| 700 | 1 | 0 | |a Aryogi, A. |e author |
| 700 | 1 | 0 | |a Pamungkas, D. |e author |
| 245 | 0 | 0 | |a Association of GHR|AluI gene polymorphism with body weight parameters in Grati-PO cattle |
| 260 | |b Diponegoro University, |c 2021-12-02. | ||
| 500 | |a https://ejournal.undip.ac.id/index.php/jitaa/article/view/36665 | ||
| 520 | |a The growth hormone receptor (GHR) gene is member of the class I cytokine receptor family that important in growth regulation including in cattle. This study aimed to analyze the association between GHR|AluI gene with body weight, parameters in Grati-PO cattle population. A total of 304 blood samples were collected from the experimental station at the Beef Cattle Research Station, which were also equipped with 304 phenotypic data. DNA was extracted using a zymo extraction kit. Detection of of the polymorphism of GHR gene using PCR-RFLP method with AluI restriction enzymes. polymorphism indicators include genotype frequency, allele frequency, Hardy-Weinberg Equilibrium, observed heterozygosity (Ho), expected heterozygosity (He), polymorphism information content (PIC) and number of effective alleles (Ne). Association analysis was carried out using a linear mixed model. The performance of birth weight, weaning weight, yearling weight and 18 months weight were 25.4 + 0.2 kg; 113.8 + 2.3 kg; 159.9 + 2.7 kg and 213.7 + 3.6 kg, respectively. The result of association analysis was significant (P<0.05) on weaning weight, yearling weight and 18 months weight. It could be concluded that the GHR gene has potential to be a candidate genetic marker for growth traits in Grati-PO cattle. | ||
| 540 | |a Copyright (c) 2021 Journal of the Indonesian Tropical Animal Agriculture | ||
| 546 | |a eng | ||
| 690 | |a Body weight; Growth hormone receptor; Polymorphism; PO-Grati cattle | ||
| 655 | 7 | |a info:eu-repo/semantics/article |2 local | |
| 655 | 7 | |a info:eu-repo/semantics/publishedVersion |2 local | |
| 655 | 7 | |a Peer-reviewed Article |2 local | |
| 786 | 0 | |n Journal of the Indonesian Tropical Animal Agriculture; Vol 46, No 4 (2021): December; 272-281 | |
| 786 | 0 | |n 2460-6278 | |
| 786 | 0 | |n 2087-8273 | |
| 787 | 0 | |n https://ejournal.undip.ac.id/index.php/jitaa/article/view/36665/pdf | |
| 856 | 4 | 1 | |u https://ejournal.undip.ac.id/index.php/jitaa/article/view/36665/pdf |z Get Fulltext |