The Pangenome : Diversity, Dynamics and Evolution of Genomes

This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology...

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Other Authors: Tettelin, Hervé (Editor), Medini, Duccio (Editor)
Format: Book Chapter
Published: Cham Springer Nature 2020
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245 1 0 |a The Pangenome : Diversity, Dynamics and Evolution of Genomes 
260 |a Cham  |b Springer Nature  |c 2020 
300 |a 1 electronic resource (307 p.) 
506 0 |a Open Access  |2 star  |f Unrestricted online access 
520 |a This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book's respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics. 
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650 7 |a Evolution  |2 bicssc 
650 7 |a Applied mathematics  |2 bicssc 
650 7 |a Ecological science, the Biosphere  |2 bicssc 
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653 |a Microbial Genetics and Genomics 
653 |a Evolutionary Biology 
653 |a Genetics and Population Dynamics 
653 |a Microbial Ecology 
653 |a Human Genetics 
653 |a Genetics and Genomics 
653 |a Comparative genomics 
653 |a Metagenomics 
653 |a Microbial Population Analysis 
653 |a Pangenome Profile 
653 |a Supra-Genome Analysis 
653 |a Adaptive Evolution 
653 |a Computational Tools 
653 |a Bioinformatic Genomics 
653 |a Core Dispensable Genome 
653 |a Selection, Recombination, Composition 
653 |a Acquired Resistance 
653 |a Bacterial Species Concept 
653 |a Genomic Diversity 
653 |a Bacterial Ecology, Microevolution 
653 |a Open Access 
653 |a Pan-metagenomics 
653 |a Pan-microbiomics 
653 |a Pan-epigenome 
653 |a Gene Transfer 
653 |a Pan-phenomes 
653 |a Microbiology (non-medical) 
653 |a Genetics (non-medical) 
653 |a Evolution 
653 |a Applied mathematics 
653 |a Ecological science, the Biosphere 
653 |a Medical genetics 
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