Chapter 13 Targeting Tumor Perfusion and Oxygenation Modulates Hypoxia and Cancer Sensitivity to Radiotherapy and Systemic Therapies
Hypoxia, a partial pressure of oxygen (pO2) below physiological needs, is a limiting factor affecting the efficiency of radiotherapy. Indeed, the reaction of reactive oxygen species (ROS, produced by water radiolysis) with DNA is readily reversible unless oxygen stabilizes the DNA lesion. While no...
Збережено в:
Автор: | Jordan, Bénédicte F. (auth) |
---|---|
Інші автори: | Sonveaux, Pierre (auth) |
Формат: | Частина з книги |
Опубліковано: |
InTechOpen
2011
|
Предмети: | |
Онлайн доступ: | Get Fullteks DOAB: description of the publication |
Теги: |
Додати тег
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|
Схожі ресурси
-
Tumor Hypoxia: Impact in Tumorigenesis, Diagnosis, Prognosis and Therapeutics
за авторством: Christian R. Gomez
Опубліковано: (2017) -
Image-Guided Radiotherapy for Effective Radiotherapy Delivery
за авторством: Nam Phong Nguyen
Опубліковано: (2016) -
Combinatorial Approaches to Enhance Anti-Tumor Immunity: Focus on Immune Checkpoint Blockade Therapy
Опубліковано: (2019) -
Controversies and Perspectives in the Use of Postoperative Radiotherapy for Prostate Cancer
за авторством: Alan Dal Pra
Опубліковано: (2018) -
Hypoxia-Inducible Factors : Regulation and Therapeutic Potential
Опубліковано: (2022)