Chapter 13 Targeting Tumor Perfusion and Oxygenation Modulates Hypoxia and Cancer Sensitivity to Radiotherapy and Systemic Therapies
Hypoxia, a partial pressure of oxygen (pO2) below physiological needs, is a limiting factor affecting the efficiency of radiotherapy. Indeed, the reaction of reactive oxygen species (ROS, produced by water radiolysis) with DNA is readily reversible unless oxygen stabilizes the DNA lesion. While no...
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主要作者: | Jordan, Bénédicte F. (auth) |
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其他作者: | Sonveaux, Pierre (auth) |
格式: | 本书章节 |
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InTechOpen
2011
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在线阅读: | Get Fullteks DOAB: description of the publication |
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