Chapter 13 Targeting Tumor Perfusion and Oxygenation Modulates Hypoxia and Cancer Sensitivity to Radiotherapy and Systemic Therapies

Hypoxia, a partial pressure of oxygen (pO2) below physiological needs, is a limiting factor affecting the efficiency of radiotherapy. Indeed, the reaction of reactive oxygen species (ROS, produced by water radiolysis) with DNA is readily reversible unless oxygen stabilizes the DNA lesion. While no...

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Detalles Bibliográficos
Autor Principal:	Jordan, Bénédicte F. (auth)
Outros autores:	Sonveaux, Pierre (auth)
Formato:	Capítulo de libro
Publicado:	InTechOpen 2011
Subjects:	Science: general issues tumor systematic therapies hypoxia radiotherapy cancer sensitivity Blood Hemodynamics Magnetic resonance imaging Neoplasm Oxygen Perfusion Radiation therapy Vasodilation
Acceso en liña:	Get Fullteks DOAB: description of the publication
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Chapter 13 Targeting Tumor Perfusion and Oxygenation Modulates Hypoxia and Cancer Sensitivity to Radiotherapy and Systemic Therapies

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