Alterations of Epigenetics and MicroRNAs in Cancer and Cancer Stem Cell

Studies have shown that alterations of epigenetics and microRNAs (miRNAs) play critical roles in the initiation and progression of human cancer. Epigenetic silencing of tumor suppressor genes in cancer cells is generally mediated by DNA hypermethylation of CpG island promoter and histone modificatio...

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Bibliographic Details
Main Author: Yoshimasa Saito (auth)
Format: Book Chapter
Published: Frontiers Media SA 2014
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