Biomimetic Radical Chemistry and Applications
The enormous importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted a strong interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an i...
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| Format: | Book Chapter |
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MDPI - Multidisciplinary Digital Publishing Institute
2020
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| Online Access: | Get Fullteks DOAB: description of the publication |
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| LEADER | 05422naaaa2201465uu 4500 | ||
|---|---|---|---|
| 001 | doab_20_500_12854_42284 | ||
| 005 | 20210211 | ||
| 020 | |a books978-3-03928-393-4 | ||
| 020 | |a 9783039283934 | ||
| 020 | |a 9783039283927 | ||
| 024 | 7 | |a 10.3390/books978-3-03928-393-4 |c doi | |
| 041 | 0 | |a English | |
| 042 | |a dc | ||
| 100 | 1 | |a Chatgilialoglu, Chryssostomos |4 auth | |
| 245 | 1 | 0 | |a Biomimetic Radical Chemistry and Applications |
| 260 | |b MDPI - Multidisciplinary Digital Publishing Institute |c 2020 | ||
| 300 | |a 1 electronic resource (300 p.) | ||
| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a The enormous importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted a strong interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment that is suitably designed to be in strict connection with cellular conditions. This Special Issue gives the reader a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to also be used as traces for the discovery of some relevant biological processes. Several subjects are presented, with 12 articles and 6 reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications, and bioinspired synthesis, having "free radicals" as a common denominator. | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by-nc-nd/4.0/ |2 cc |4 https://creativecommons.org/licenses/by-nc-nd/4.0/ | ||
| 546 | |a English | ||
| 653 | |a gold nanoparticles | ||
| 653 | |a inhomogeneous reactions | ||
| 653 | |a chemical nuclease | ||
| 653 | |a liposomal somatostatin | ||
| 653 | |a replication fork stalling | ||
| 653 | |a lipid bilayer membranes | ||
| 653 | |a 2c-3e S?S-bonded intermediates | ||
| 653 | |a cell micropolarity maps | ||
| 653 | |a protein labeling | ||
| 653 | |a time-resolved spectroscopy | ||
| 653 | |a 1 | ||
| 653 | |a pulse radiolysis | ||
| 653 | |a nucleosides | ||
| 653 | |a 2-thiouracil | ||
| 653 | |a [1 | ||
| 653 | |a lipidomics | ||
| 653 | |a radicals | ||
| 653 | |a reactive aldehydes | ||
| 653 | |a iron porphyrin | ||
| 653 | |a photolysis | ||
| 653 | |a oxidative damage | ||
| 653 | |a free fatty acids | ||
| 653 | |a charge transfer | ||
| 653 | |a fragmentation | ||
| 653 | |a biomimetic radical reaction | ||
| 653 | |a sulfones | ||
| 653 | |a bioinspired chemical catalysis | ||
| 653 | |a genomic and epigenomic instability | ||
| 653 | |a ATRPase | ||
| 653 | |a DNA methylation | ||
| 653 | |a oxononenal | ||
| 653 | |a trans lipid | ||
| 653 | |a copper | ||
| 653 | |a membrane fluidity maps | ||
| 653 | |a mitochondrial uncoupling protein | ||
| 653 | |a heme | ||
| 653 | |a thiyl radicals | ||
| 653 | |a oxidation | ||
| 653 | |a anomeric spironucleosides | ||
| 653 | |a protein stability | ||
| 653 | |a laser flash photolysis | ||
| 653 | |a type 2 diabetes | ||
| 653 | |a stationary radiolysis | ||
| 653 | |a confocal microscopy | ||
| 653 | |a iron(IV)-oxo | ||
| 653 | |a 5]-radical translocation | ||
| 653 | |a diabetes | ||
| 653 | |a DNA hole transfer | ||
| 653 | |a free radical oxidation | ||
| 653 | |a radical reaction | ||
| 653 | |a kinetic studies | ||
| 653 | |a circular dichroism | ||
| 653 | |a catalase activity | ||
| 653 | |a thiobases | ||
| 653 | |a intercalation | ||
| 653 | |a electron transfer | ||
| 653 | |a iron-mediated ATRP | ||
| 653 | |a Fenton reaction | ||
| 653 | |a EPR spectroscopy | ||
| 653 | |a glycogen phosphorylase | ||
| 653 | |a azidoalkylation | ||
| 653 | |a free radicals | ||
| 653 | |a gamma radiolysis | ||
| 653 | |a quantum dynamics | ||
| 653 | |a hydrogen peroxide | ||
| 653 | |a carboazidation | ||
| 653 | |a ?OH and ?N3 radicals | ||
| 653 | |a 5? | ||
| 653 | |a oligonucleotides | ||
| 653 | |a Raman spectroscopy | ||
| 653 | |a azides | ||
| 653 | |a peroxidation | ||
| 653 | |a photo-ionization | ||
| 653 | |a guanine quadruplexes | ||
| 653 | |a 8-cyclopurines | ||
| 653 | |a beta cells | ||
| 653 | |a cross-link | ||
| 653 | |a miRNAs | ||
| 653 | |a oxidative DNA damage | ||
| 653 | |a DNA damage | ||
| 653 | |a modified nucleosides | ||
| 653 | |a Julia-Kocienski olefination | ||
| 653 | |a DNA oxidation | ||
| 653 | |a therapeutic proteins | ||
| 653 | |a DNA replication stress | ||
| 653 | |a electron holes | ||
| 653 | |a singlet oxygen | ||
| 653 | |a radiosensitizers | ||
| 653 | |a cellular response | ||
| 653 | |a hydroxynonenal | ||
| 653 | |a isomerization | ||
| 653 | |a ?-radiolysis | ||
| 653 | |a histone modifications | ||
| 653 | |a 8-oxo-dG | ||
| 653 | |a 6-dioxa-4-azaspiro[4.5]decane | ||
| 653 | |a retarded delivery | ||
| 653 | |a reaction mechanism | ||
| 653 | |a DNA | ||
| 653 | |a albumin | ||
| 653 | |a TD-DFT methods | ||
| 653 | |a nucleobase derivatives | ||
| 653 | |a bio-mimicking catalyst | ||
| 856 | 4 | 0 | |a www.oapen.org |u https://mdpi.com/books/pdfview/book/2134 |7 0 |z Get Fullteks |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/42284 |7 0 |z DOAB: description of the publication |