Carbonic Anhydrases and Metabolism

Carbonic anhydrases (CAs; EC 4.2.1.1) are metalloenzymes present in all kingdoms of life, as they equilibrate the reaction between three simple but essential chemical species: CO2, bicarbonate, and protons. Discovered more than 80 years ago, in 1933, these enzymes have been extensively investigated...

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Bibliographic Details
Main Author:	Supuran, Claudiu T. (auth)
Format:	Book Chapter
Published:	MDPI - Multidisciplinary Digital Publishing Institute 2019
Subjects:	antibiotic inhibitors glaucoma metabolic role inhibitor engineered bacteria carbonic anhydrase inhibitors drug discovery enzyme inhibition V-ATPases photosynthesis Chlamydomonas reinhardtii metalloenzymes CO2 capture bicarbonate benzamide hypoxia antibody model alga cancer therapeutics CA gene family resistance isoforms IX and XII cancer metabolism MMP14 carbonic anhydrase IX carboxylation bacterial enzymes antitumor agent metabolism activator bacterial carbonic anhydrases amine amino acid pH regulation proton pump inhibitors pathogens sulfonamide metastasis hypoxic tumor carbonic anhydrase pH carbonic anhydrases protozoan integrin Entamoeba histolytica tumors human isoform acidity invasion radiation tumor carbonic anhydrase XII transporter migration cancer tumor microenvironment
Online Access:	Get Fullteks DOAB: description of the publication
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Carbonic Anhydrases and Metabolism

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