Cellular and molecular mechanisms of motor neuron death in amyotrophic lateral sclerosis

Cellular and molecular mechanisms of motor neuron death in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS), which was described since 1869 by Jean Martin Charcot, is a devastating neurodegenerative disease characterized by the selective and progressive loss of upper and lower motor neurons of the cerebral cortex, brainstem and the spinal cord. The cognitive process is...

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Hlavní autor: Ricardo Tapia (auth)
Médium: Kapitola
Vydáno: Frontiers Media SA 2015
Témata:
trophic factors
motor neuron degeneration
skeletal
neuroinflammation
muscle
genetic expression
spinal cord
amyotrophic lateral sclerosis (ALS)
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