The Coevolution of IDO1 and AhR in the Emergence of Regulatory T Cells in Mammals
Indoleamine 2,3-dioxygenase (IDO1) is an ancestral enzyme that, initially confined to the regulation of tryptophan availability in local tissue microenvironments, is now considered to play a wider role that extends to homeostasis and plasticity of the immune system. Thus IDO biology has implications...
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Main Author: | Ursula Grohmann (auth) |
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Other Authors: | Paolo Puccetti (auth) |
Format: | Book Chapter |
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Frontiers Media SA
2016
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Online Access: | Get Fullteks DOAB: description of the publication |
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