DNA Replication Controls
The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a...
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| Format: | Book Chapter |
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MDPI - Multidisciplinary Digital Publishing Institute
2017
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| Subjects: | |
| Online Access: | Get Fullteks DOAB: description of the publication |
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| Summary: | The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a hallmark of cancers and aging-related disorders. |
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| Physical Description: | 1 electronic resource (X, 304 p.) |
| ISBN: | books978-3-03842-569-4 9783038425694 9783038425687 |
| Access: | Open Access |