DNA Replication Controls
The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a...
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| Format: | Book Chapter |
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MDPI - Multidisciplinary Digital Publishing Institute
2017
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| Subjects: | |
| Online Access: | Get Fullteks DOAB: description of the publication |
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| LEADER | 01652naaaa2200373uu 4500 | ||
|---|---|---|---|
| 001 | doab_20_500_12854_45329 | ||
| 005 | 20210211 | ||
| 020 | |a books978-3-03842-569-4 | ||
| 020 | |a 9783038425694 | ||
| 020 | |a 9783038425687 | ||
| 024 | 7 | |a 10.3390/books978-3-03842-569-4 |c doi | |
| 041 | 0 | |a English | |
| 042 | |a dc | ||
| 100 | 1 | |a Eishi Noguchi (Ed.) |4 auth | |
| 245 | 1 | 0 | |a DNA Replication Controls |
| 260 | |b MDPI - Multidisciplinary Digital Publishing Institute |c 2017 | ||
| 300 | |a 1 electronic resource (X, 304 p.) | ||
| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a hallmark of cancers and aging-related disorders. | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by-nc-nd/4.0/ |2 cc |4 https://creativecommons.org/licenses/by-nc-nd/4.0/ | ||
| 546 | |a English | ||
| 653 | |a DNA helicase | ||
| 653 | |a DNA replication | ||
| 653 | |a replication stress | ||
| 653 | |a replication checkpoint | ||
| 653 | |a DNA polymerase | ||
| 653 | |a telomere replication | ||
| 653 | |a cancer | ||
| 653 | |a genomic instability | ||
| 653 | |a DNA repair | ||
| 653 | |a replisome | ||
| 653 | |a translesion synthesis | ||
| 856 | 4 | 0 | |a www.oapen.org |u http://www.mdpi.com/books/pdfview/book/453 |7 0 |z Get Fullteks |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/45329 |7 0 |z DOAB: description of the publication |