Emerging Enterobacteriaceae Infections: Antibiotic Resistance and Novel Treatment Options

Enterobacteriaceae are spread worldwide and the diseases they cause may be fatal especially in immunocompromised patients. Moreover, the high prevalence of ESBL producing Salmonella and Shigella species diseases worldwide suggests major underlying safety issues. According to the World Health Organiz...

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Main Author: Ghassan M. Matar (auth)
Format: Book Chapter
Published: Frontiers Media SA 2017
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Online Access:Get Fullteks
DOAB: description of the publication
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100 1 |a Ghassan M. Matar  |4 auth 
245 1 0 |a Emerging Enterobacteriaceae Infections: Antibiotic Resistance and Novel Treatment Options 
260 |b Frontiers Media SA  |c 2017 
300 |a 1 electronic resource (115 p.) 
506 0 |a Open Access  |2 star  |f Unrestricted online access 
520 |a Enterobacteriaceae are spread worldwide and the diseases they cause may be fatal especially in immunocompromised patients. Moreover, the high prevalence of ESBL producing Salmonella and Shigella species diseases worldwide suggests major underlying safety issues. According to the World Health Organization (WHO), 2015, approximately 220 million children contract diarrhoeal diseases every year and 96 000 die. As a result, the increase in single or multi drug-resistant foodborne bacterial pathogens is of major public health concern. Moreover, resistance to antimicrobials was found among Salmonella spp and Campylobacter spp from animals and food, and since fluoroquinolones became licensed for use in animal foods, especially for poultry, the rate of fluoroquinolone resistant Salmonella spp and Campylobacter spp in animals and human food, and then in human infections, rapidly increased. To that purpose, the findings of the conducted studies in the book chapters, 1) highlight surveillance studies reporting the occurrence and distribution of resistance to antimicrobial agents, namely, to third generation cephalosporins, carbapenems and fluoroquinolones, 2) describe the mechanisms of transmission of resistance determinants from animals, food products and clinical specimens, that allow implementation of appropriate measures to control their spread and adopt appropriate therapeutic measures, and 3) provide treatment options, useful to medical practice. 
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546 |a English 
653 |a Resistance 
653 |a Treatment 
653 |a ESBLs 
653 |a surveillance 
653 |a carbapenemases 
653 |a Enterobacteriaceae 
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