Entwicklung eines mikrofluidischen Zweikammer-Chipsystems mit integrierter Sensorik für die Anwendung in der Tumorforschung

We have developed a microfluidic two-layered channel system based on polycarbonate to investigate the transmigration of cancer cells under flow conditions and defined shear rate using live cell microscopy. The two layers are separated by a porous membrane with an endothelial monolayer on top of the...

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গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Rajabi, Taleieh (auth)
বিন্যাস: গ্রন্থের অধ্যায়
প্রকাশিত: KIT Scientific Publishing 2014
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DOAB: description of the publication
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020 |a KSP/1000041112 
020 |a 9783731502203 
024 7 |a 10.5445/KSP/1000041112  |c doi 
041 0 |a German 
042 |a dc 
100 1 |a Rajabi, Taleieh  |4 auth 
245 1 0 |a Entwicklung eines mikrofluidischen Zweikammer-Chipsystems mit integrierter Sensorik für die Anwendung in der Tumorforschung 
260 |b KIT Scientific Publishing  |c 2014 
300 |a 1 electronic resource (IX, 163 p. p.) 
506 0 |a Open Access  |2 star  |f Unrestricted online access 
520 |a We have developed a microfluidic two-layered channel system based on polycarbonate to investigate the transmigration of cancer cells under flow conditions and defined shear rate using live cell microscopy. The two layers are separated by a porous membrane with an endothelial monolayer on top of the membrane to mimic the blood vessel wall. To extend the measuring capabilities of our microfluidic chip, gold electrodes were structured on the membrane using optical lithography and chemical etching. 
540 |a Creative Commons  |f https://creativecommons.org/licenses/by-sa/4.0/  |2 cc  |4 https://creativecommons.org/licenses/by-sa/4.0/ 
546 |a German 
653 |a membrane 
653 |a Krebszellen 
653 |a SensorikCancer cell 
653 |a Metastasierung 
653 |a Mikrofluidik 
653 |a Blutgefäß 
653 |a sensors 
653 |a Membran 
653 |a Blood vessel 
653 |a Impedanz 
653 |a microfluidic 
653 |a Impedance 
856 4 0 |a www.oapen.org  |u https://www.ksp.kit.edu/9783731502203  |7 0  |z Get Fullteks 
856 4 0 |a www.oapen.org  |u https://directory.doabooks.org/handle/20.500.12854/46581  |7 0  |z DOAB: description of the publication