Experimental Animal Models of Human Diseases - An Effective Therapeutic Strategy

The world has recorded losses in terms of human life as well as extensive time spent in experimentation with development of new drugs, elucidation of disease mechanism(s), and therapeutic agent discovery. Ethical and legal issues cojoin in slowing down scientific discoveries in medicine and biology....

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Main Author: Ibeh Bartholomew (auth)
Format: Book Chapter
Published: IntechOpen 2018
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Online Access:Get Fullteks
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020 |a 66030 
020 |a 9781789231649 
020 |a 9781789231656 
024 7 |a 10.5772/66030  |c doi 
041 0 |a English 
042 |a dc 
100 1 |a Ibeh Bartholomew  |4 auth 
245 1 0 |a Experimental Animal Models of Human Diseases - An Effective Therapeutic Strategy 
260 |b IntechOpen  |c 2018 
300 |a 1 electronic resource (408 p.) 
506 0 |a Open Access  |2 star  |f Unrestricted online access 
520 |a The world has recorded losses in terms of human life as well as extensive time spent in experimentation with development of new drugs, elucidation of disease mechanism(s), and therapeutic agent discovery. Ethical and legal issues cojoin in slowing down scientific discoveries in medicine and biology. The past two (2) decades, therefore, have seen tremendous attempts that largely are successful in developing animal models with the characteristics of mimicking, approximating, or expressing transplanted human organs/tissues. These models or rather approaches seem to be fast, cost-effective, and easy to maintain compared to primates. This book is a collection of expert essays on animal models of human diseases of global interest. A visible objective of the book is to provide real-time experimental approach to scientists, clinicians, ethicists, medicolegal/medical jurisprudence workers, immunologists, postgraduate students, and vaccinologists and informative and multidisciplinary approach for the identification of new therapeutic targets and biomarkers using animal models as well as investigating the pathogenesis and therapeutic strategies of human diseases. An increased understanding of the genetic, molecular, and cellular mechanisms responsible for the development of human diseases has laid out the foundation for the development of rational therapies mainly with animal models. 
540 |a All rights reserved  |4 http://oapen.org/content/about-rights 
546 |a English 
653 |a Life Sciences 
653 |a Animal Biology 
653 |a Agricultural and Biological Sciences 
653 |a Anthrozoology 
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856 4 0 |a www.oapen.org  |u https://directory.doabooks.org/handle/20.500.12854/47203  |7 0  |z DOAB: description of the publication