Grand Celebration: 10th Anniversary of the Human Genome Project

In 1990, scientists began working together on one of the largest biological research projects ever proposed. The project proposed to sequence the three billion nucleotides in the human genome. The Human Genome Project took 13 years and was completed in April 2003, at a cost of approximately three bi...

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Published: MDPI - Multidisciplinary Digital Publishing Institute 2016
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020 |a 9783038421726 
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041 0 |a English 
042 |a dc 
245 1 0 |a Grand Celebration: 10th Anniversary of the Human Genome Project 
260 |b MDPI - Multidisciplinary Digital Publishing Institute  |c 2016 
300 |a 1 electronic resource (274 p.) 
506 0 |a Open Access  |2 star  |f Unrestricted online access 
520 |a In 1990, scientists began working together on one of the largest biological research projects ever proposed. The project proposed to sequence the three billion nucleotides in the human genome. The Human Genome Project took 13 years and was completed in April 2003, at a cost of approximately three billion dollars. It was a major scientific achievement that forever changed the understanding of our own nature. The sequencing of the human genome was in many ways a triumph for technology as much as it was for science. From the Human Genome Project, powerful technologies have been developed (e.g., microarrays and next generation sequencing) and new branches of science have emerged (e.g., functional genomics and pharmacogenomics), paving new ways for advancing genomic research and medical applications of genomics in the 21st century. The investigations have provided new tests and drug targets, as well as insights into the basis of human development and diagnosis/treatment of cancer and several mysterious humans diseases. This genomic revolution is prompting a new era in medicine, which brings both challenges and opportunities. Parallel to the promising advances over the last decade, the study of the human genome has also revealed how complicated human biology is, and how much remains to be understood. The legacy of the understanding of our genome has just begun. To celebrate the 10th anniversary of the essential completion of the Human Genome Project, in April 2013 Genes launched this Special Issue, which highlights the recent scientific breakthroughs in human genomics, with a collection of papers written by authors who are leading experts in the field. 
540 |a Creative Commons  |f https://creativecommons.org/licenses/by/4.0/  |2 cc  |4 https://creativecommons.org/licenses/by/4.0/ 
546 |a English 
653 |a gene structure 
653 |a human genetics 
653 |a genomic medicine 
653 |a functional genomics 
653 |a genetics and genomics of model organisms for human diseases 
653 |a cancer genetics 
653 |a molecular basis of human genetic disease 
653 |a stem cells in human genetics 
653 |a pharmacogenomics and gene therapy 
653 |a gene therapy and personal genomics 
653 |a expression and regulation 
653 |a genetic and genomic technologies 
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