MicroRNAs: Novel Biomarkers and Therapeutic Targets for Human Cancers
MicroRNAs (miRNAs) constitute a large family of small, approximately 20-22-nucleotide, non-coding RNAs that are involved in gene regulation, mainly at the post-transcriptional level. Multiple lines of evidence have indicated that miRNAs play important roles in the maintenance of biological homeostas...
সংরক্ষণ করুন:
| প্রধান লেখক: | |
|---|---|
| অন্যান্য লেখক: | |
| বিন্যাস: | গ্রন্থের অধ্যায় |
| প্রকাশিত: |
MDPI - Multidisciplinary Digital Publishing Institute
2018
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | Get Fullteks DOAB: description of the publication |
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| LEADER | 02096naaaa2200337uu 4500 | ||
|---|---|---|---|
| 001 | doab_20_500_12854_53438 | ||
| 005 | 20210211 | ||
| 020 | |a books978-3-03897-253-2 | ||
| 020 | |a 9783038972525 | ||
| 020 | |a 9783038972532 | ||
| 024 | 7 | |a 10.3390/books978-3-03897-253-2 |c doi | |
| 041 | 0 | |a English | |
| 042 | |a dc | ||
| 100 | 1 | |a Ryou-u Takahashi (Ed.) |4 auth | |
| 700 | 1 | |a Takahiro Ochiya (Ed.) |4 auth | |
| 245 | 1 | 0 | |a MicroRNAs: Novel Biomarkers and Therapeutic Targets for Human Cancers |
| 260 | |b MDPI - Multidisciplinary Digital Publishing Institute |c 2018 | ||
| 300 | |a 1 electronic resource (272 p.) | ||
| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a MicroRNAs (miRNAs) constitute a large family of small, approximately 20-22-nucleotide, non-coding RNAs that are involved in gene regulation, mainly at the post-transcriptional level. Multiple lines of evidence have indicated that miRNAs play important roles in the maintenance of biological homeostasis and that aberrant expression levels of miRNAs are involved in the onset of many diseases, including cancer. In various types of cancer, miRNAs play important roles in tumor initiation and development. Recently, miRNAs have been demonstrated to also be secreted via small endosome-derived vesicles called exosomes-which are derived from multiple cell types-including immunocytes and cancer cells. Exosomal miRNAs exert important functions in cell-to-cell communication and have been investigated as prognostic and diagnostic biomarkers. | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by-nc-nd/4.0/ |2 cc |4 https://creativecommons.org/licenses/by-nc-nd/4.0/ | ||
| 546 | |a English | ||
| 653 | |a tumor initiation and development | ||
| 653 | |a cancer therapy | ||
| 653 | |a circulating microRNA | ||
| 653 | |a microRNA | ||
| 653 | |a diagnosis | ||
| 653 | |a biomarker | ||
| 653 | |a exosome | ||
| 856 | 4 | 0 | |a www.oapen.org |u https://www.mdpi.com/books/pdfview/book/800 |7 0 |z Get Fullteks |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/53438 |7 0 |z DOAB: description of the publication |