Modeling of electrophysiology and tension development in the human heart

Comprehension of the beating of the human heart is important for cardiac research and will improve many clinical applications. Simulations based on models describing cardiac electro-mechanics can acquire insights into this behavior. This work focuses on the mathematical reconstruction of electrophys...

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Bibliographic Details
Main Author: Seemann, Gunnar (auth)
Format: Book Chapter
Published: KIT Scientific Publishing 2005
Subjects:
Online Access:Get Fullteks
DOAB: description of the publication
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001 doab_20_500_12854_53695
005 20210211
020 |a KSP/1000003545 
020 |a 393730066X 
024 7 |a 10.5445/KSP/1000003545  |c doi 
041 0 |a German 
042 |a dc 
100 1 |a Seemann, Gunnar  |4 auth 
245 1 0 |a Modeling of electrophysiology and tension development in the human heart 
260 |b KIT Scientific Publishing  |c 2005 
300 |a 1 electronic resource (XI, 233 p. p.) 
506 0 |a Open Access  |2 star  |f Unrestricted online access 
520 |a Comprehension of the beating of the human heart is important for cardiac research and will improve many clinical applications. Simulations based on models describing cardiac electro-mechanics can acquire insights into this behavior. This work focuses on the mathematical reconstruction of electrophysiology, excitation conduction, and tension development in the human heart on the cellular and the tissue level. The tissue models represent accurate anatomical shapes of the atria and the ventricles and incorporate electrophysiological heterogeneity and anisotropic conduction. The simulations comprehend the physiological behavior of the ventricles and of the atrium including the sinoatrial node as well as pathological cases like ventricular and atrial fibrillation and genetic defects in ionic channels. 
540 |a Creative Commons  |f https://creativecommons.org/licenses/by-nc-nd/4.0/  |2 cc  |4 https://creativecommons.org/licenses/by-nc-nd/4.0/ 
546 |a German 
653 |a Heterogenität 
653 |a Gewebe 
653 |a Kardiologie 
653 |a Computersimulation 
653 |a Ionenkanal 
653 |a Aktionspotenzial 
653 |a Erregung 
653 |a Elektrophysiologie 
653 |a Muskelfaser 
653 |a Kraft 
653 |a Tachykardie 
856 4 0 |a www.oapen.org  |u https://www.ksp.kit.edu/393730066X  |7 0  |z Get Fullteks 
856 4 0 |a www.oapen.org  |u https://directory.doabooks.org/handle/20.500.12854/53695  |7 0  |z DOAB: description of the publication