Molecular imaging in Parkinson's disease
The present work explores brain functional changes in drug-naïve Parkinson's disease (PD) patients by means of molecular imaging techniques. Thirty-one consecutive drug-naïve PD patients from the Neurological Clinic of the University of Flor-ence underwent clinical assessment, neuropsychologi...
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| Format: | Book Chapter |
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Firenze University Press
2011
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| Online Access: | Get Fullteks DOAB: description of the publication |
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| LEADER | 01598naaaa2200205uu 4500 | ||
|---|---|---|---|
| 001 | doab_20_500_12854_53840 | ||
| 005 | 20210211 | ||
| 020 | |a 978-88-6655-041-9 | ||
| 020 | |a 9788866550419 | ||
| 024 | 7 | |a 10.36253/978-88-6655-041-9 |c doi | |
| 042 | |a dc | ||
| 100 | 1 | |a Cristina Polito |4 auth | |
| 245 | 1 | 0 | |a Molecular imaging in Parkinson's disease |
| 260 | |b Firenze University Press |c 2011 | ||
| 300 | |a 1 electronic resource (68 p.) | ||
| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a The present work explores brain functional changes in drug-naïve Parkinson's disease (PD) patients by means of molecular imaging techniques. Thirty-one consecutive drug-naïve PD patients from the Neurological Clinic of the University of Flor-ence underwent clinical assessment, neuropsychological assessment, MRI, [123I]FP-CIT SPECT, [18F]FDG PET. First, [18F]FDG-PET was employed to identify in drug-naïve PD patients brain metabolic alteration uniquely related to disease process and not modulated by anti-parkinsonian therapeutic intervention. Second, [18F]FDG-PET and [123I]FP-CIT SPECT were employed together to explore the early functional changes in brain function related to dopaminergic depletion in the putamen and in the caudate nucleus. | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by-nd/4.0/ |2 cc |4 https://creativecommons.org/licenses/by-nd/4.0/ | ||
| 856 | 4 | 0 | |a www.oapen.org |u https://www.fupress.com/redir.ashx?RetUrl=5052.pdf |7 0 |z Get Fullteks |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/53840 |7 0 |z DOAB: description of the publication |