Neuropeptide GPCRs in Neuroendocrinology

The human genome encompasses ~ 860 G protein-coupled receptors (GPCRs) including 374 non-chemosensory GPCRs. Half of these latter GPCRs recognize (neuro)peptides as natural ligands. GPCRs thus play a pivotal role in neuroendocrine communication. In particular, GPCRs are involved in the neuroendocrin...

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Main Author: Jae Young Seong (auth)
Other Authors: Hubert Vaudry (auth)
Format: Book Chapter
Published: Frontiers Media SA 2014
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Online Access:Get Fullteks
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100 1 |a Jae Young Seong  |4 auth 
700 1 |a Hubert Vaudry  |4 auth 
245 1 0 |a Neuropeptide GPCRs in Neuroendocrinology 
260 |b Frontiers Media SA  |c 2014 
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520 |a The human genome encompasses ~ 860 G protein-coupled receptors (GPCRs) including 374 non-chemosensory GPCRs. Half of these latter GPCRs recognize (neuro)peptides as natural ligands. GPCRs thus play a pivotal role in neuroendocrine communication. In particular, GPCRs are involved in the neuroendocrine control of feeding behavior, reproduction, growth, hydromineral homeostasis and stress response. GPCRs are also major drug targets and hence possess a strong potential for the development of innovative pharmaceuticals. The aim of this Research Topic was to assemble a series of review articles and original research papers on neuropeptide GPCRs and their ligands that would illustrate the different facets of the studies currently conducted in this domain. 
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546 |a English 
653 |a Transduction pathways 
653 |a G protein-coupled receptors 
653 |a Neuroendocrinology 
653 |a Heptahelical receptors 
653 |a Neuropeptides 
653 |a Signaling mechanisms 
653 |a Biologically active peptides 
653 |a seven-transmembrane domain receptors 
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