NK Cell Subsets in Health and Disease: New Developments

Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory...

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Main Author: Emanuela Marcenaro (auth)
Other Authors: Luigi D. Notarangelo (auth), Jordan S. Orange (auth), Eric Vivier (auth)
Format: Book Chapter
Published: Frontiers Media SA 2017
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Online Access:Get Fullteks
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020 |a 978-2-88945-350-4 
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024 7 |a 10.3389/978-2-88945-350-4  |c doi 
041 0 |a English 
042 |a dc 
100 1 |a Emanuela Marcenaro  |4 auth 
700 1 |a Luigi D. Notarangelo  |4 auth 
700 1 |a Jordan S. Orange  |4 auth 
700 1 |a Eric Vivier  |4 auth 
245 1 0 |a NK Cell Subsets in Health and Disease: New Developments 
260 |b Frontiers Media SA  |c 2017 
300 |a 1 electronic resource (243 p.) 
506 0 |a Open Access  |2 star  |f Unrestricted online access 
520 |a Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology. 
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546 |a English 
653 |a ILCs 
653 |a inflammation 
653 |a NK cell subsets 
653 |a immunotherapy 
653 |a anti-viral responses 
653 |a anti-tumor responses 
653 |a immune checkpoints 
856 4 0 |a www.oapen.org  |u https://www.frontiersin.org/research-topics/4350/nk-cell-subsets-in-health-and-disease-new-developments  |7 0  |z Get Fullteks 
856 4 0 |a www.oapen.org  |u https://directory.doabooks.org/handle/20.500.12854/54691  |7 0  |z DOAB: description of the publication