Oncolytic Viruses - Genetically Engineering the Future of Cancer Therapy

The ability to genetically engineer oncolytic viruses in order to minimize side effects and improve the selective targeting of tumor cells has opened up novel opportunities for treating cancer. Understanding the mechanisms involved and the complex interaction between the viruses and the immune syste...

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Bibliographic Details
Main Author: Benjamin Gesundheit (auth)
Other Authors: Joshua P. Rosenzweig (auth)
Format: Book Chapter
Published: Frontiers Media SA 2017
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Online Access:Get Fullteks
DOAB: description of the publication
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020 |a 978-2-88945-358-0 
020 |a 9782889453580 
024 7 |a 10.3389/978-2-88945-358-0  |c doi 
041 0 |a English 
042 |a dc 
100 1 |a Benjamin Gesundheit  |4 auth 
700 1 |a Joshua P. Rosenzweig  |4 auth 
245 1 0 |a Oncolytic Viruses - Genetically Engineering the Future of Cancer Therapy 
260 |b Frontiers Media SA  |c 2017 
300 |a 1 electronic resource (193 p.) 
506 0 |a Open Access  |2 star  |f Unrestricted online access 
520 |a The ability to genetically engineer oncolytic viruses in order to minimize side effects and improve the selective targeting of tumor cells has opened up novel opportunities for treating cancer. Understanding the mechanisms involved and the complex interaction between the viruses and the immune system will undoubtedly help guide the development of new strategies. Theranostic biomarkers to monitor these therapies in clinical trials serve an important need in this innovative field and demand further research. 
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546 |a English 
653 |a theranostic nanomedicine 
653 |a cancer immunotherapy 
653 |a oncolytic viruses 
653 |a antitumor immunity 
653 |a oncoimmunology 
653 |a gene expression 
653 |a transgenes 
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