Organogenesis From Development to Disease
During embryonic development there are many processes that must take place to produce a viable and healthy fetus. Alterations in the cellular and/or molecular interactions within any particular organ can cause catastrophic defects leading to defective organogenesis and death of the embryo. Even slig...
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| Format: | Book Chapter |
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Frontiers Media SA
2017
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| Online Access: | Get Fullteks DOAB: description of the publication |
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| LEADER | 02360naaaa2200385uu 4500 | ||
|---|---|---|---|
| 001 | doab_20_500_12854_55410 | ||
| 005 | 20210211 | ||
| 020 | |a 978-2-88945-318-4 | ||
| 020 | |a 9782889453184 | ||
| 024 | 7 | |a 10.3389/978-2-88945-318-4 |c doi | |
| 041 | 0 | |a English | |
| 042 | |a dc | ||
| 100 | 1 | |a Misty Good |4 auth | |
| 700 | 1 | |a Seppo Vainio |4 auth | |
| 700 | 1 | |a Sunder Sims-Lucas |4 auth | |
| 245 | 1 | 0 | |a Organogenesis From Development to Disease |
| 260 | |b Frontiers Media SA |c 2017 | ||
| 300 | |a 1 electronic resource (110 p.) | ||
| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a During embryonic development there are many processes that must take place to produce a viable and healthy fetus. Alterations in the cellular and/or molecular interactions within any particular organ can cause catastrophic defects leading to defective organogenesis and death of the embryo. Even slight malformations of the organs can cause developmental reprogramming and increase the likelihood of adult onset diseases. The use of experimental animals with genetic mutations that mimic many human conditions has lead to significant scientific advancement of these complex and multifaceted diseases. Furthermore, the utilization of organ culture systems has made for profound insights into the formation of organs. Over recent years, the technology related to molecular profiling and imaging of developing organs has dramatically improved, leading to the identification of subtle genetic and phenotypic alterations. This research topic will focus on the area of organ formation and modeling of human developmental diseases. | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by/4.0/ |2 cc |4 https://creativecommons.org/licenses/by/4.0/ | ||
| 546 | |a English | ||
| 653 | |a Disease Models | ||
| 653 | |a kidney development | ||
| 653 | |a Bladder innervation | ||
| 653 | |a Animal | ||
| 653 | |a Bowel disease | ||
| 653 | |a Inflammation | ||
| 653 | |a Developmental Biology | ||
| 653 | |a Diabetes Mellitus | ||
| 653 | |a Organogenesis | ||
| 653 | |a Type 1 | ||
| 653 | |a bone mineralization | ||
| 856 | 4 | 0 | |a www.oapen.org |u https://www.frontiersin.org/research-topics/3607/organogenesis-from-development-to-disease |7 0 |z Get Fullteks |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/55410 |7 0 |z DOAB: description of the publication |