Pharmaceutical Crystals

Pharmaceutical Crystals

The crystalline state is the most commonly used essential solid active pharmaceutical ingredient (API). The characterization of pharmaceutical crystals encompasses many scientific disciplines, but the core is crystal structure analysis, which reveals the molecular structure of essential pharmaceutic...

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Autore principale:	Uekusa, Hidehiro (auth)
Altri autori:	Yonemochi, Etsuo (auth)
Natura:	Capitolo di libro
Pubblicazione:	MDPI - Multidisciplinary Digital Publishing Institute 2020
Soggetti:	crystal structure analysis n/a famotidine solution crystallization salt optimization structure determination from powder diffraction data Hirshfeld surface analysis DFT molecular docking study melting diagram dehydration hygroscopicity HBV Benzodioxole pharmaceutical crystals 4-b]indol-4-one pyrimidin-4(3H)-one liquid assisted grinding HOMO-LUMO dissolution cocrystal formation Raman spectroscopy carbamazepine hydrogen bonding 3 ondansetron physicochemical properties solubility succinic acid cocrystal adefovir dipivoxil hepatitis B polymorphs hydrogen-bond-acceptance ability DFT study Nitrofurantoin-4-dimethylaminopyridine (NF-DMAP) salt photostability on-line monitoring 5-dihydro-4H-pyrimido[5 Imidazole Semicarbazone crystal habit Crystal structure solvent-mediated polymorphic transformation ticagrelor hydrate pharmaceutical cocrystal malonic acid 1H-indole reactivity descriptors famoxadone crystal structure dicarboxylic acid hydrogen bond saccharin
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