Pharmaceutical Crystals

Pharmaceutical Crystals

The crystalline state is the most commonly used essential solid active pharmaceutical ingredient (API). The characterization of pharmaceutical crystals encompasses many scientific disciplines, but the core is crystal structure analysis, which reveals the molecular structure of essential pharmaceutic...

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Autore principale: Uekusa, Hidehiro (auth)
Altri autori: Yonemochi, Etsuo (auth)
Natura: Capitolo di libro
Pubblicazione: MDPI - Multidisciplinary Digital Publishing Institute 2020
Soggetti:
crystal structure analysis
n/a
famotidine
solution crystallization
salt optimization
structure determination from powder diffraction data
Hirshfeld surface analysis
DFT
molecular docking study
melting diagram
dehydration
hygroscopicity
HBV
Benzodioxole
pharmaceutical crystals
4-b]indol-4-one
pyrimidin-4(3H)-one
liquid assisted grinding
HOMO-LUMO
dissolution
cocrystal formation
Raman spectroscopy
carbamazepine
hydrogen bonding
3
ondansetron
physicochemical properties
solubility
succinic acid
cocrystal
adefovir dipivoxil
hepatitis B
polymorphs
hydrogen-bond-acceptance ability
DFT study
Nitrofurantoin-4-dimethylaminopyridine (NF-DMAP) salt
photostability
on-line monitoring
5-dihydro-4H-pyrimido[5
Imidazole
Semicarbazone
crystal habit
Crystal structure
solvent-mediated polymorphic transformation
ticagrelor
hydrate
pharmaceutical cocrystal
malonic acid
1H-indole
reactivity descriptors
famoxadone
crystal structure
dicarboxylic acid
hydrogen bond
saccharin
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