Recent Progress in Solid Dispersion Technology
Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD's natural non-equilibrium. However,...
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| Format: | Book Chapter |
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MDPI - Multidisciplinary Digital Publishing Institute
2019
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| Online Access: | Get Fullteks DOAB: description of the publication |
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| LEADER | 03569naaaa2200901uu 4500 | ||
|---|---|---|---|
| 001 | doab_20_500_12854_57786 | ||
| 005 | 20210212 | ||
| 020 | |a books978-3-03921-502-7 | ||
| 020 | |a 9783039215010 | ||
| 020 | |a 9783039215027 | ||
| 024 | 7 | |a 10.3390/books978-3-03921-502-7 |c doi | |
| 041 | 0 | |a English | |
| 042 | |a dc | ||
| 100 | 1 | |a Kawakami, Kohsaku |4 auth | |
| 245 | 1 | 0 | |a Recent Progress in Solid Dispersion Technology |
| 260 | |b MDPI - Multidisciplinary Digital Publishing Institute |c 2019 | ||
| 300 | |a 1 electronic resource (204 p.) | ||
| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD's natural non-equilibrium. However, recent significant advances in ASD knowledge and technology may enable a much broader use of ASD technology. This Special Issue, which includes 3 reviews and 6 original articles, focuses on recent progresses in ASD technology in hopes of helping to accelerate developmental studies in the pharmaceutical industry. In striving for a deep understanding of ASD non-equilibrium behavior, the Special issue also delves into and makes progress in the theory of soft-matter dynamics. | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by-nc-nd/4.0/ |2 cc |4 https://creativecommons.org/licenses/by-nc-nd/4.0/ | ||
| 546 | |a English | ||
| 653 | |a thermodynamic modeling | ||
| 653 | |a molecular dynamics simulation | ||
| 653 | |a poorly soluble drugs | ||
| 653 | |a amorphous solid dispersions | ||
| 653 | |a dissolution enhancement | ||
| 653 | |a crystallization tendency | ||
| 653 | |a continuous processing | ||
| 653 | |a stability | ||
| 653 | |a milling | ||
| 653 | |a granulation | ||
| 653 | |a thermal analysis | ||
| 653 | |a amorphous | ||
| 653 | |a ball milling | ||
| 653 | |a pharmaceutical glass | ||
| 653 | |a dissolution | ||
| 653 | |a rebamipide | ||
| 653 | |a poloxamer | ||
| 653 | |a classification | ||
| 653 | |a polyelectrolytes | ||
| 653 | |a amorphisation | ||
| 653 | |a self-assembly | ||
| 653 | |a dissolution rate | ||
| 653 | |a miscibility | ||
| 653 | |a bioavailability | ||
| 653 | |a solubility | ||
| 653 | |a evaporation | ||
| 653 | |a mesoporous | ||
| 653 | |a polyelectrolyte excipient matrix | ||
| 653 | |a polymer | ||
| 653 | |a bicaludamide | ||
| 653 | |a phase diagram | ||
| 653 | |a Weibull dissolution model | ||
| 653 | |a spectroscopic techniques | ||
| 653 | |a anticancer drugs | ||
| 653 | |a manufacturing methods | ||
| 653 | |a nucleation | ||
| 653 | |a molecular complex | ||
| 653 | |a nanoaggregates | ||
| 653 | |a enrofloxacin | ||
| 653 | |a accelerated stability test | ||
| 653 | |a solubility enhancement | ||
| 653 | |a amorphous solid dispersion | ||
| 653 | |a tadalafil | ||
| 653 | |a process development | ||
| 653 | |a amorphous polymeric salt | ||
| 653 | |a Wood's apparatus | ||
| 653 | |a hot melt extrusion | ||
| 653 | |a solid dispersions | ||
| 653 | |a intrinsic dissolution rate | ||
| 653 | |a solid dispersion | ||
| 653 | |a interaction | ||
| 653 | |a crystallization | ||
| 653 | |a spray drying | ||
| 653 | |a characterization | ||
| 653 | |a ciprofloxacin | ||
| 856 | 4 | 0 | |a www.oapen.org |u https://mdpi.com/books/pdfview/book/1607 |7 0 |z Get Fullteks |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/57786 |7 0 |z DOAB: description of the publication |