Role of DNA Methyltransferases in the Epigenome
DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generati...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Book Chapter |
| Published: |
MDPI - Multidisciplinary Digital Publishing Institute
2020
|
| Subjects: | |
| Online Access: | Get Fullteks DOAB: description of the publication |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| LEADER | 03031naaaa2200673uu 4500 | ||
|---|---|---|---|
| 001 | doab_20_500_12854_58578 | ||
| 005 | 20210212 | ||
| 020 | |a books978-3-03928-021-6 | ||
| 020 | |a 9783039280216 | ||
| 020 | |a 9783039280209 | ||
| 024 | 7 | |a 10.3390/books978-3-03928-021-6 |c doi | |
| 041 | 0 | |a English | |
| 042 | |a dc | ||
| 100 | 1 | |a Jeltsch, Albert |4 auth | |
| 700 | 1 | |a Gowher, Humaira |4 auth | |
| 245 | 1 | 0 | |a Role of DNA Methyltransferases in the Epigenome |
| 260 | |b MDPI - Multidisciplinary Digital Publishing Institute |c 2020 | ||
| 300 | |a 1 electronic resource (150 p.) | ||
| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generation and maintenance of the phenotypic diversity of human cell types. Recent years have brought spectacular advances in our understanding of the mechanism, function and regulation of DNA methyltransferases through their interaction with other epigenome modifications, chromatin factors and post-translational modifications, which are described in this Special Issue of Genes. Manuscripts are specifically addressing describing the targeting and regulation of DNA methyltransferases by interacting factors and their roles in cellular differentiation and the development of diseases. Prof. Dr. Albert Jeltsch and Prof. Dr. Humaira Gowher, Guest Editors | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by-nc-nd/4.0/ |2 cc |4 https://creativecommons.org/licenses/by-nc-nd/4.0/ | ||
| 546 | |a English | ||
| 653 | |a DNMTs | ||
| 653 | |a n/a | ||
| 653 | |a histone modification | ||
| 653 | |a TBRS | ||
| 653 | |a DNA methyltransferases | ||
| 653 | |a autoinhibition | ||
| 653 | |a epigenetics | ||
| 653 | |a DNMT | ||
| 653 | |a cell identity | ||
| 653 | |a embryogenesis | ||
| 653 | |a dwarfism | ||
| 653 | |a DNMT3B | ||
| 653 | |a germ cells | ||
| 653 | |a HSAN1E | ||
| 653 | |a USP7 | ||
| 653 | |a DNMT3A | ||
| 653 | |a DNA methyltransferase | ||
| 653 | |a gene expression | ||
| 653 | |a DNMT1 | ||
| 653 | |a de novo DNA methylation | ||
| 653 | |a DNA methyltransferase structure | ||
| 653 | |a UHRF1 | ||
| 653 | |a DNA methyltransferase mechanism | ||
| 653 | |a allosteric regulation | ||
| 653 | |a rare diseases | ||
| 653 | |a DNA Methylation | ||
| 653 | |a maintenance DNA methylation | ||
| 653 | |a DNA methylation | ||
| 653 | |a ADCA-DN | ||
| 653 | |a PCC/PGL | ||
| 653 | |a ubiquitination | ||
| 653 | |a TETs | ||
| 653 | |a DNA methyltransferase function | ||
| 653 | |a molecular epigenetics | ||
| 653 | |a DNA methyltransferase regulation | ||
| 856 | 4 | 0 | |a www.oapen.org |u https://mdpi.com/books/pdfview/book/2060 |7 0 |z Get Fullteks |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/58578 |7 0 |z DOAB: description of the publication |