The Second Life of Natural Killer (NK) Cells

Natural Killer (NK) cells are innate lymphocytes, now recognized as members of a larger family of "Innate lymphoid cells" (ILCs). Both murine and human NK cells are well characterized effector cells with cytotoxic as well as cytokine production ability which mainly react in response to mic...

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Bibliographic Details
Main Author: Joseph C. Sun (auth)
Other Authors: Marco Colonna (auth), Chiara Romagnani (auth)
Format: Book Chapter
Published: Frontiers Media SA 2018
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Online Access:Get Fullteks
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020 |a 978-2-88945-546-1 
020 |a 9782889455461 
024 7 |a 10.3389/978-2-88945-546-1  |c doi 
041 0 |a English 
042 |a dc 
100 1 |a Joseph C. Sun  |4 auth 
700 1 |a Marco Colonna  |4 auth 
700 1 |a Chiara Romagnani  |4 auth 
245 1 0 |a The Second Life of Natural Killer (NK) Cells 
260 |b Frontiers Media SA  |c 2018 
300 |a 1 electronic resource (118 p.) 
506 0 |a Open Access  |2 star  |f Unrestricted online access 
520 |a Natural Killer (NK) cells are innate lymphocytes, now recognized as members of a larger family of "Innate lymphoid cells" (ILCs). Both murine and human NK cells are well characterized effector cells with cytotoxic as well as cytokine production ability which mainly react in response to microbial and cell stress stimuli, thus playing a central role in the defense against pathogen infection, in tumor surveillance and in regulating immune homeostasis. Despite these established concepts, our understanding of the complexity of NK cells, also in view of their developmental and functional relationship with other ILC subsets, is only recently emerging. This Research Topic highlights the recent advances in NK cell (and ILC) research in human and mouse from basic research to clinical applications. 
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546 |a English 
653 |a natural killer cells 
653 |a ILC 
653 |a NK cells 
653 |a immune therapy 
653 |a viral infection 
653 |a NK cell education 
653 |a immunotherapy 
653 |a MHC-I 
653 |a cancer 
653 |a immune regulation 
653 |a adaptive immunity 
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856 4 0 |a www.oapen.org  |u https://directory.doabooks.org/handle/20.500.12854/59076  |7 0  |z DOAB: description of the publication