Structural and computational glycobiology: immunity and infection

Interest in understanding the biological role of carbohydrates has increased significantly over the last 20 years. The use of structural techniques to understand carbohydrate-protein recognition is still a relatively young area, but one that is of emerging importance. The high flexibility of carbohy...

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Main Author: Mark Agostino (auth)
Other Authors: Elizabeth Yuriev (auth)
Format: Book Chapter
Published: Frontiers Media SA 2015
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Online Access:Get Fullteks
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041 0 |a English 
042 |a dc 
100 1 |a Mark Agostino  |4 auth 
700 1 |a Elizabeth Yuriev  |4 auth 
245 1 0 |a Structural and computational glycobiology: immunity and infection 
260 |b Frontiers Media SA  |c 2015 
300 |a 1 electronic resource (102 p.) 
506 0 |a Open Access  |2 star  |f Unrestricted online access 
520 |a Interest in understanding the biological role of carbohydrates has increased significantly over the last 20 years. The use of structural techniques to understand carbohydrate-protein recognition is still a relatively young area, but one that is of emerging importance. The high flexibility of carbohydrates significantly complicates the determination of high quality structures of their complexes with proteins. Specialized techniques are often required to understand the complexity of carbohydrate recognition by proteins. In this Research Topic, we will focus on structural and computational approaches to understanding carbohydrate recognition by proteins involved in immunity and infection. Particular areas of focus include cancer immunotherapeutics, carbohydrate-lectin interactions, glycosylation and glycosyltransferases. 
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546 |a English 
653 |a infection 
653 |a signaling 
653 |a molecular modeling 
653 |a cancer immunotherapy 
653 |a lectins 
653 |a molecular recognition 
653 |a structural biology 
653 |a glycobiology 
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