A study on cholinergic signal transduction pathways involved in short term and long term memory formation in the rat hippocampus : Molecular and cellular alterations underlying memory impairments in animal models of neurodegeneration
Neurodegenerative processes alter neuronal and glial physiology and cause cognitive and mnemonic impairments. Aim of this PhD thesis is to investigate the involvement of the cholinergic system and the role of mTOR pathway in the mechanisms of memory encoding in the hippocampus and to study the patho...
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| Format: | Book Chapter |
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Firenze University Press
2015
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| Online Access: | Get Fullteks DOAB: description of the publication |
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| LEADER | 01655naaaa2200205uu 4500 | ||
|---|---|---|---|
| 001 | doab_20_500_12854_60212 | ||
| 005 | 20210212 | ||
| 020 | |a 978-88-6655-941-2 | ||
| 020 | |a 9788866559412 | ||
| 024 | 7 | |a 10.36253/978-88-6655-941-2 |c doi | |
| 042 | |a dc | ||
| 100 | 1 | |a Daniele Lana |4 auth | |
| 245 | 1 | 0 | |a A study on cholinergic signal transduction pathways involved in short term and long term memory formation in the rat hippocampus : Molecular and cellular alterations underlying memory impairments in animal models of neurodegeneration |
| 260 | |b Firenze University Press |c 2015 | ||
| 300 | |a 1 electronic resource (136 p.) | ||
| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a Neurodegenerative processes alter neuronal and glial physiology and cause cognitive and mnemonic impairments. Aim of this PhD thesis is to investigate the involvement of the cholinergic system and the role of mTOR pathway in the mechanisms of memory encoding in the hippocampus and to study the pathophysiological processes at the base of the cognitive impairments in different experimental models of neurodegeneration: in particular normal brain aging, neuroin ammation and chronic cerebral hypoperfusion. These mechanisms are studied focusing on the morpho-functional alterations in the neuron-astrocytemicroglia triad. | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by/4.0/ |2 cc |4 https://creativecommons.org/licenses/by/4.0/ | ||
| 856 | 4 | 0 | |a www.oapen.org |u https://www.fupress.com/redir.ashx?RetUrl=3049_8684.pdf |7 0 |z Get Fullteks |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/60212 |7 0 |z DOAB: description of the publication |