Mitochondria and Brain Disorders
The mitochondrion is a unique and ubiquitous organelle that contains its own genome, encoding essential proteins that are major components of the respiratory chain and energy production system. Mitochondria play a dominant role in the life and function of eukaryotic cells including neurons and glia,...
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| Format: | Book Chapter |
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IntechOpen
2020
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| Online Access: | Get Fullteks DOAB: description of the publication |
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| LEADER | 01986naaaa2200301uu 4500 | ||
|---|---|---|---|
| 001 | doab_20_500_12854_67348 | ||
| 005 | 20210420 | ||
| 020 | |a intechopen.77668 | ||
| 020 | |a 9781789855326 | ||
| 020 | |a 9781789855319 | ||
| 020 | |a 9781789856538 | ||
| 024 | 7 | |a 10.5772/intechopen.77668 |c doi | |
| 041 | 0 | |a English | |
| 042 | |a dc | ||
| 072 | 7 | |a MFN |2 bicssc | |
| 100 | 1 | |a Baloyannis, Stavros |4 edt | |
| 700 | 1 | |a Baloyannis, Stavros |4 oth | |
| 245 | 1 | 0 | |a Mitochondria and Brain Disorders |
| 260 | |b IntechOpen |c 2020 | ||
| 300 | |a 1 electronic resource (124 p.) | ||
| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a The mitochondrion is a unique and ubiquitous organelle that contains its own genome, encoding essential proteins that are major components of the respiratory chain and energy production system. Mitochondria play a dominant role in the life and function of eukaryotic cells including neurons and glia, as their survival and activity depend upon mitochondrial energy production and supply. Besides energy production, mitochondria also play a vital role in calcium homeostasis and may induce apoptosis by excitotoxicity. Mitochondrial dysfunction is related to common neurological diseases, such as Parkinson's disease, Alzheimer's disease, Friedreich's ataxia, Huntington's disease, and Multiple Sclerosis. An efficient treatment of mitochondrial dysfunction would open new horizons in the therapeutic perspectives of a substantial number of inflammatory and degenerative neurological disorders. | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by/3.0/ |2 cc |4 https://creativecommons.org/licenses/by/3.0/ | ||
| 546 | |a English | ||
| 650 | 7 | |a Medical genetics |2 bicssc | |
| 653 | |a Medical genetics | ||
| 856 | 4 | 0 | |a www.oapen.org |u https://mts.intechopen.com/storage/books/7850/authors_book/authors_book.pdf |7 0 |z Get Fullteks |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/67348 |7 0 |z DOAB: description of the publication |