Aggregatibacter actinomycetemcomitans—Gram-Negative Bacterial Pathogen

Aggregatibacter actinomycetemcomitans—Gram-Negative Bacterial Pathogen

Aggregatibacter actinomycetemcomitans is a well-studied Gram-negative bacterium that can often be found in the oral cavity of young individuals. It has several virulence factors and a large genetic diversity, which results in both harmless and highly virulent genotypes. To determine the virulence po...

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Opis bibliograficzny
Kolejni autorzy: Johansson, Anders (Redaktor), DiRienzo, Joseph M. (Redaktor)
Format: Rozdział
Wydane: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Hasła przedmiotowe:
Research & information: general
Biology, life sciences
Aggregatibacter actinomycetemcomitans
cagE
virB1
virB4
genotype
virulence
mRNA assay
quantitative ELISA
cell lysis assay
leukotoxin
JP2 genotype
cytolethal distending toxin
lipopolysaccharides
cytokine binding factors
horizontal gene transfer
outer membrane vesicles
biofilm
proteomic
adherence
endocarditis
fimbriae
JP2
periodontitis
taxonomy
core and accessory genes
average nucleotide identity
principal component analysis
keratins
organotypic gingival mucosa
A. actinomycetemcomitans
RNA-Seq
genomic islands
core genes
accessory genes
stress
nutrient limitation
differentially expressed genes.
lymphocytes
apoptosis
RTX toxin
localized aggressive periodontitis
LFA-1
leukotoxin (LtxA)
endocytosis
n/a
JP2 clone of Aggregatibacter actinomycetemcomitans
JP2 in Caucasian
microbiological diagnosis
adjunctive antibiotics
localized aggressive periodontitis: animal studies: human studies
landscape ecology
damage/response framework
bacteremia
horseshoe crab
Origanum vulgare
essential oil
antimicrobial activity
minimum inhibitory concentration
minimal bactericidal concentration
cytotoxicity
leukotoxin neutralization
inflammasome
immune response
periodontal disease
proteomics
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