Aggregatibacter actinomycetemcomitans—Gram-Negative Bacterial Pathogen

Aggregatibacter actinomycetemcomitans is a well-studied Gram-negative bacterium that can often be found in the oral cavity of young individuals. It has several virulence factors and a large genetic diversity, which results in both harmless and highly virulent genotypes. To determine the virulence po...

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Tác giả khác:	Johansson, Anders (Biên tập viên), DiRienzo, Joseph M. (Biên tập viên)
Định dạng:	Chương của sách
Được phát hành:	Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Những chủ đề:	Research & information: general Biology, life sciences Aggregatibacter actinomycetemcomitans cagE virB1 virB4 genotype virulence mRNA assay quantitative ELISA cell lysis assay leukotoxin JP2 genotype cytolethal distending toxin lipopolysaccharides cytokine binding factors horizontal gene transfer outer membrane vesicles biofilm proteomic adherence endocarditis fimbriae JP2 periodontitis taxonomy core and accessory genes average nucleotide identity principal component analysis keratins organotypic gingival mucosa A. actinomycetemcomitans RNA-Seq genomic islands core genes accessory genes stress nutrient limitation differentially expressed genes. lymphocytes apoptosis RTX toxin localized aggressive periodontitis LFA-1 leukotoxin (LtxA) endocytosis n/a JP2 clone of Aggregatibacter actinomycetemcomitans JP2 in Caucasian microbiological diagnosis adjunctive antibiotics localized aggressive periodontitis: animal studies: human studies landscape ecology damage/response framework bacteremia horseshoe crab Origanum vulgare essential oil antimicrobial activity minimum inhibitory concentration minimal bactericidal concentration cytotoxicity leukotoxin neutralization inflammasome immune response periodontal disease proteomics
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Aggregatibacter actinomycetemcomitans—Gram-Negative Bacterial Pathogen

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