Cocrystal Applications in Drug Delivery

In 2015, the first pharmaceutical cocrystal was approved by the FDA. Since then, the number of cocrystals on the market and in the development pipeline has been slowly but steadily growing. It is now well established that cocrystals are a versatile new approach to oral drug formulation. This Reprint...

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Další autoři:	Erxleben, Andrea (Editor)
Médium:	Kapitola
Vydáno:	Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Témata:	Research & information: general nitazoxanide cocrystals multicomponent crystals dissolution behavior supersaturated formulations crystallization inhibitors drug-polymer interactions nano co-crystals crystal engineering polydispersity index zeta potential particle size zidovudine lamivudine HIV/AIDS sonochemistry imidazole N-oxides barbituric acid thiobarbituric acid pharmaceutical cocrystals mechanochemistry solid state NMR X-ray Diffraction design of experiments Quality by Design cocrystal compaction nanoindentation slip plane tabletability surface topology interparticulate bonding area interparticulate bonding strength nefiracetam solid state solubility dissolution rate stability formulation diclofenac sodium L-proline salt cocrystal multicomponent crystal monohydrate tetrahydrate dissolution itraconazole terephthalic acid crystal structure solid-state thermal analysis wettability n/a
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Cocrystal Applications in Drug Delivery

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