Drug Delivery of siRNA Therapeutics

Drug Delivery of siRNA Therapeutics

The new frontier of pharmaceutical sciences is gene therapy, which is the use of molecules able to interact directly with the expression of the genetic material of the patient as well as of the disease-causing guest (bacteria, virus, parasites, and tumor cells). Among the molecules of interest for g...

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Altri autori: Lamberti, Gaetano (Redattore), Angela Barba, Anna (Redattore)
Natura: Capitolo di libro
Pubblicazione: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
Soggetti:
Medicine
oligonucleotide delivery
light-activated release
intracellular release
liposome
indocyanine green
drug co-delivery
methotrexate
siRNA
antitumor effect
mixed micelles
targeted delivery system
cationic liposome
folate
folate receptor
cationic cholesterol derivative
siRNA delivery
gene knockdown
tumor-targeting
VEGFA
VEGFR1
endoglin
peptide
angiogenesis
gene silencing
migration
proliferation
endothelial cells
RNAi therapeutics
amphiphilic dendrons
PAMAM dendrimers
self-assembling
nanovectors
covalent dendrimers
NABDs
liposomes
clinical trials
drug delivery
nanoparticle
carbonate apatite
ERBB2
AKT
breast cancer
ovarian cancer
polymer
lipid
delivery
poly(ethylene) imine
PEI
RNA
tyrosine-modification
tumor xenograft
magnetic nanoparticle
iron oxide
BCL2
BIRC5/survivin
oral cancer
aptamers
cancer
nanoparticles
STAT6
polyaspartamide
pegylation
polyamine
polyplexes
asthma
n/a
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