3D Printing of Pharmaceuticals and Drug Delivery Devices

The 3D printing (3DP) process was patented in 1986; however, only in the last decade has it begun to be used for medical applications, as well as in the fields of prosthetics, bio-fabrication, and pharmaceutical printing. 3DP or additive manufacturing (AM) is a family of technologies that implement...

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Další autoři:	Lamprou, Dimitrios A. (Editor)
Médium:	Kapitola
Vydáno:	Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
Témata:	Medicine digital pharmacy fused deposition modeling 3D printing modified drug release personalized medicines telemedicine three dimensional printing additive manufacturing 3D printed drug products printlets personalised medicines personalized pharmaceuticals multiple units spheroids beads acetaminophen 3D printing fused filament fabrication lignin antioxidant materials wound dressing modified release filament extrusion fused layer modeling theophylline high API load three-dimensional printing fixed-dose combinations tablets multiple-layer dosage forms stereolithography vat polymerisation fused deposition modeling polylactic acid chemical modification MTT assay biofilm formation warfarin semisolid extrusion 3D printing inkjet printing orodispersible film oral powder pediatric hospital pharmacy personalized medicine on-demand manufacturing drug delivery micromedicine drug development micro-swimmer micro-implant oral dosages microneedle high-precision targeting controlled release geometry resolution feature size release profile vascularization digital light processing technology neural networks optimization prediction FMD pregabalin gastric floating complex structures patient-specific structural design gums Fused Deposition Modeling 3D Printing processing parameters pharmaceutical quality control hot-melt extrusion solid dosage forms 3D printed oral dosage forms sustained drug release tablets photopolymerization paracetamol (acetaminophen) aspirin (acetylsalicylic acid) amorphous solid dispersion poor solubility fixed dose combination stencil printing pharmacoprinting orodispersible discs orodisperible films floating systems pulsatile release chronotherapeutic delivery wound-healing 3D bio-printing pectin propolis cyclodextrin 3D bio-inks fused deposition modelling extrusion vaginal meshes mechanical properties drug release anti-infective devices pelvic organ prolapse stress urinary incontinence gastro-retentive floating system dissolution kinetics implantable devices subcutaneous biodegradable prolonged drug delivery polymers pharmaceuticals extrusion-based 3D printing fused deposition modeling (FDM) pressure-assisted microsyringe (PAM) materials process 3D bioprinting polymeric ink pseudo-bone implantable scaffold computer-aided design (CAD) design bioprinting computer-aided design (CAD) pharmaceutics
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Shrnutí:	The 3D printing (3DP) process was patented in 1986; however, only in the last decade has it begun to be used for medical applications, as well as in the fields of prosthetics, bio-fabrication, and pharmaceutical printing. 3DP or additive manufacturing (AM) is a family of technologies that implement layer-by-layer processes in order to fabricate physical models based on a computer aided design (CAD) model. 3D printing permits the fabrication of high degrees of complexity with great reproducibility in a fast and cost-effective fashion. 3DP technology offers a new paradigm for the direct manufacture of individual dosage forms and has the potential to allow for variations in size and geometry as well as control dose and release behavior. Furthermore, the low cost and ease of use of 3DP systems means that the possibility of manufacturing medicines and medical devices at the point of dispensing or at the point of use could become a reality. 3DP thus offers the perfect innovative manufacturing route to address the critical capability gap that hinders the widespread exploitation of personalized medicines for molecules that are currently not easy to deliver. This Special Issue will address new developments in the area of 3D printing and bioprinting for drug delivery applications, covering the recent advantages and future directions of additive manufacturing for pharmaceutical products.
Fyzický popis:	1 electronic resource (436 p.)
ISBN:	books978-3-03936-424-4 9783039364237 9783039364244
Přístup:	Open Access

3D Printing of Pharmaceuticals and Drug Delivery Devices

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