Recent Advances and Clinical Outcomes of Kidney Transplantation

Advances in immunosuppression and kidney transplant techniques have led to significant improvements in the short-term survival of the renal allograft. Long-term graft survival, however, has relatively lagged behind and has now become one of the main problems in kidney transplantation. In this Specia...

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Bibliographic Details
Other Authors:	Cheungpasitporn, Wisit (Editor), Thongprayoon, Charat (Editor), Leeaphorn, Napat (Editor)
Format:	Book Chapter
Published:	Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
Subjects:	Medicine malondialdehyde oxidative stress new-onset diabetes renal transplantation BK virus BK virus nephropathy kidney allograft transplantation Alport syndrome children autosomal dominant polycystic kidney disease epidemiology hospitalization kidney transplantation subarachnoid hemorrhage malignancy post-transplant malignancy renal cell carcinoma meta-analysis systematic reviews tacrolimus C/D-ratio pharmacokinetics opportunistic infection allograft survival urological complications ureteric stent urinary tract infection timing of removal living donor ethnicity age obesity genetic relationship donor/recipient atypical hemolytic uremic syndrome eculizumab glucose intolerance insulin secretion insulin resistance oral glucose tolerance test healthy subject hyperchloremia kidney graft dysfunction living donor kidney transplantation Uropathogenic E. coli UPEC phylogeny genomics antibiotic resistance virulence traits night-time renal transplantation graft survival patient survival/outcome surgical complications acute rejection lymphocyte CD45RC Belatacept cardiovascular high risk outcome machine perfusion organ preservation temperature hypothermic normothermic transplant proton-pump inhibitors iron iron deficiency polyomavirus BKV kidney glomerulus BKVAN nephropathy fluid management delayed graft function goal-directed fluid therapy calcineurin inhibitor nephrotoxcity C/D ratio tacrolimus metabolism ADPKD native nephrectomy patient outcome perioperative complications epidermal growth factor creatinine graft failure renal transplantation. new onset diabetes after renal transplantation single nucleotide polymorphisms n/a urinary biomarkers α-GST π-GST nephrotoxicity urinary excretion of N1-methylnicotinamide mortality niacin status dietary intake tryptophan vitamin B3 Kidney transplant vitamin C cancer mortality oxidative stress. mycophenolic acid immunosuppression plasmapheresis oxalate hyperoxaluria kidney transplant recipients post-transplantation diabetes mellitus all-cause mortality cardiovascular mortality infectious mortality magnesium hypomagnesaemia cancer kidney transplant survival living kidney donation living-donor kidney transplantation beliefs inequity ischemia reperfusion injury innate immune system adaptive immune system apoptosis necrosis hypoxic inducible factor endothelial dysfunction proton pump inhibitor transplant rejection GFR insulin-like growth factor 1 growth hormone muscle mass patient survival physical activity renal transplant recipients kidney transplant (KT) donor-specific antibodies (DSA) C3d-binding assay antibody-mediated rejection (AMR) arsenic diet fish consumption post-transplant diabetes mellitus N1-methyl-2-pyridone-5-carboxamide N1-methylnicotinamide urinary excretion kidney function biomarker branched chain amino acids posttransplant diarrhea methanogenesis Methanosphaera stadtmanae mucins sulfate-reducing bacteria acute humoral rejection first-line therapy outcomes proteasome inhibitor renal transplant transplant recipients calcineurin inhibitors FK506 pharmacokinetic fast tacrolimus metabolizers
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Summary:	Advances in immunosuppression and kidney transplant techniques have led to significant improvements in the short-term survival of the renal allograft. Long-term graft survival, however, has relatively lagged behind and has now become one of the main problems in kidney transplantation. In this Special Issue, we discuss the recent research developments in kidney transplants that may affect long-term allografts, as well as the survival of the patient. The latest developments in living kidney donation are also explored.
Physical Description:	1 electronic resource (342 p.)
ISBN:	books978-3-03936-365-0 9783039363643 9783039363650
Access:	Open Access

Recent Advances and Clinical Outcomes of Kidney Transplantation

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