Antitumoral Properties of Natural Products

Antitumoral Properties of Natural Products

Cancer is one of the major causes of death worldwide. It is a multifactorial heterogeneous disease characterized by the transformation of normal cells into malignant cells, which acquire an uncontrolled growth, immortality, invasiveness, and ability to form distant metastasis. Natural bioactive mole...

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Övriga upphovsmän: Fabiani, Roberto (Utgivare, redaktör, sammanställare)
Materialtyp: Bokavsnitt
Publicerad: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
Ämnen:
Research & information: general
Biology, life sciences
cytotoxic activity
NCI-60 cancer cell line
pristimerin
Salacia crassifolia
Celastraceae
Brazilian Cerrado biome
Salacia elliptica
Cheiloclinium cognatum
Plenckia populnea
Aspergillus fumigatus
Cordyceps sinensis
isochromanes
chiral resolution
ECD calculation
cytotoxicity
coronarin D
JNK
osteosarcoma
Zeylenone
gastric cancer
invasion
migration
apoptosis
anti-cancer agents
anthraquinones
glycosyltransferase
Dendrobium officinale
structure elucidation
anti-tumor activity
plantation mode
AR
Ganoderma tsugae
lipogenesis
prostate cancer
SREBP-1
ursolic acid
betulinic acid
triterpenoids
necrotic
quercetin
quercetagetin
patuletin
lichen
secondary metabolites
tumidulin
stemness potential
colorectal cancer cells
oncogene
transcriptional regulation
neferine
FAK/S6K1
autophagy
human neuroblastoma cells
natural yellow Monascus pigments
water-soluble
antioxidation
MCF-7 cells
phloretin
cell proliferation
inflammation
glucose uptake
Catalpa speciosa
Taxus cuspidata
Magnolia acuminata
phenols
antioxidants
anticancer
Colocasia esculenta
food bioactive
tarin
stable nanocapsules
entrapment efficiency
no-toxicity
preclinical tests
antitumoral activity
chemotherapeutic adjuvant
grape leaves
ASE
TP
Antioxidant activities
Antiproliferative
pro-apoptotic effects
Gene expression
Nutraceuticals
Cucurbitacin B
gefitinib-resistant NSCLC
EGFR
lysosomal degradation
CIP2A
zerumbone
cancer
NF-κB
IL-6/JAK2/STAT3
Akt
FOXO1
multiple myeloma
quality control
naringenin
flavonoids
traditional preparation
cancer stem cells
phytochemicals
plant-derived foods
fruit
vegetable
cell signaling
Artemisia absinthium
endoplasmic reticulum stress
mitochondrial-dependent pathway
melanoma
bee venom
melittin
temozolomide
AKT
MAPK
antrodin C
mTOR
metabolic stability
capsazepine
inflammatory diseases
ROS
TRPV1
PI3K/AKT/mTOR
CLE-10
LC3
MDA-MB-231
lactoferrin hydrolysate
copper
manganese
gastric cancer cells
anti-cancer activity
molecular mechanism
natural product alkaloids
cephalotaxine
protein synthesis inhibition
antiproliferation agents
folk medicine
DLD-1 cells
doxorubicin
chemotherapy
drug resistance
CrataBL
glioblastoma
mesenchymal stem cells
microenvironment
plant lectin
protease inhibitor
cryptolepine
neocryptolepine
isocryptolepine
antiproliferative activity
structure activity relationships
Licochalcone A
ATM-Chk2
13-ethylberberine
mitochondrial ROS
RT-R breast cancer cells
diallyl disulfide
PI3K/Akt/mTOR pathway
Pulsatilla saponin D
SB365
glioblastoma multiforme
autophagic flux inhibition
lysosomal membrane permeabilization
mitochondrial membrane potential
CLEFMA
p38
proanthocyanins
TNF-α
lung adenocarcinoma
natural compounds
cervical cancer
cell cycle arrest
dicentrine
metastasis
glioma
semi-synthetic derivative
ingenol
Euphorbia tirucalli
protein kinase C
seaweed
porphyran
carrageenan
anti-cancer
natural products
n/a
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