Marine Bioactive Natural Product Studies-A Southern Hemisphere Perspective

Marine Bioactive Natural Product Studies-A Southern Hemisphere Perspective

The search for bioactive secondary metabolites from marine organisms has been an active area of research since the 1950s. The distinct biodiversity of the marine environment has afforded a vast array of unique secondary metabolites, many of which possess potent biological activities. This Special Is...

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Altri autori: Urban, Sylvia (Redattore)
Natura: Capitolo di libro
Pubblicazione: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
Soggetti:
Medicine
Sinularia
Alcyoniidae
anticancer activity
lobane
cembrane
diterpene
conotoxins
ShK toxin
ion channels
docking
molecular dynamics
potential of mean force
free energy perturbation
bioactivity
biosynthesis
brominated secondary metabolites
choline ester
indole
sea cucumber
viscera
saponins
mass spectrometry
MALDI
ESI
HPCPC
triterpene glycosides
structure elucidation
bioactive compounds
marine invertebrate
Echinodermata
holothurian
Cnemidocarpa stolonifera
taurine amide
PC3 cell line
immunofluorescence assay
thiaplidiaquinone
Aplidium
ascidian
thiazinoquinone
apoptosis
Jurkat
cytotoxicity
malaria
farnesyltransferase
synthesis
thiaplakortone
regioisomer
tricyclic
natural product scaffold
X-ray
crystal
Plasmodium falciparum
antiplasmodial
cephalostatin
mandelalide
methicillin resistant Staphylococcus aureus
MRSA PK
bisindole alkaloids
salternamide A (SA)
HIF-1α
PI3K/Akt/mTOR
p42/p44 MAPK
STAT3
cell death
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