The Protein Alpha-Synuclein: Its Normal Role (in Neurons) and its Role in Disease

The Protein Alpha-Synuclein: Its Normal Role (in Neurons) and its Role in Disease

The protein alpha-synuclein (α-syn) is by far the most vetted pathogenic participant in the neurodegeneration that occurs in Parkinson's disease (PD) and other synucleinopathies such as multiple system atrophy (MSA). Although the precise role of this protein in disease pathogenesis is unknown,...

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Övriga upphovsmän: Manfredsson, Fredric P. (Utgivare, redaktör, sammanställare), Perez, Ruth G. (Utgivare, redaktör, sammanställare), Martinez Sandoval, Ivette (Utgivare, redaktör, sammanställare)
Materialtyp: Bokavsnitt
Publicerad: Frontiers Media SA 2020
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Science: general issues
Neurosciences
alpha-synuclein function
alpha-synuclein aggregation
neurodegeneration
Parkinson's disease
synucleinopathies
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