The Role of Immediate Early Genes in Neuropsychiatric Illness

The search to identify the genes for mental illnesses has been complicated by the critical, yet poorly understood, role that environment plays in development of these disorders. Immediate early genes link environmental events, such as stress, to long-term changes in the brain. These genes play criti...

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Other Authors: Gallitano, Amelia L. (Editor)
Format: Book Chapter
Published: Frontiers Media SA 2020
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700 1 |a Gallitano, Amelia L.  |4 oth 
245 1 0 |a The Role of Immediate Early Genes in Neuropsychiatric Illness 
260 |b Frontiers Media SA  |c 2020 
300 |a 1 electronic resource (177 p.) 
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520 |a The search to identify the genes for mental illnesses has been complicated by the critical, yet poorly understood, role that environment plays in development of these disorders. Immediate early genes link environmental events, such as stress, to long-term changes in the brain. These genes play critical roles in numerous processes that are affected in mental illnesses including synaptic plasticity and memory, growth factor regulation, myelination and vascularization, and immune function. Thus, dysfunction in the activation of immediate early genes may explain the dual genetic and environmental etiology of these enigmatic illnesses. The current Research Topic explores the role of immediate early genes in processes that may underlie the symptoms, or risk to develop, neuropsychiatric illnesses. 
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650 7 |a Science: general issues  |2 bicssc 
650 7 |a Neurosciences  |2 bicssc 
653 |a immediate early gene 
653 |a mental disorder 
653 |a environment 
653 |a stress 
653 |a memory 
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