Preclinical Evaluation of Lipid-Based Nanosystems

Preclinical Evaluation of Lipid-Based Nanosystems

The use of lipid-based nanosystems, including lipid nanoparticles (solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC)), nanoemulsions, and liposomes, among others, is widespread. Several researchers have described the advantages of different applications of these nanosystems. Fo...

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Altri autori: Silva, Ana Catarina (Redattore), Sousa Lobo, José Manuel (Redattore)
Natura: Capitolo di libro
Pubblicazione: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Soggetti:
Technology: general issues
nanostructured lipid carriers (NLC)
formulation optimization
rivastigmine
quality by design (QbD)
nasal route
nose-to-brain
N-alkylisatin
liposome
urokinase plasminogen activator
PAI-2
SerpinB2
breast cancer
liposomes
target delivery nanosystem
FZD10 protein
colon cancer therapy
supersaturation
silica-lipid hybrid
spray drying
lipolysis
lipid-based formulation
fenofibrate
mesoporous silica
oral drug delivery
hyaluronic acid
drug release
light activation
stability
mobility
biocorona
dissolution enhancement
phospholipids
solid dosage forms
porous microparticles
nanoemulsion(s)
phase-behavior
DoE
D-optimal design
vegetable oils
non-ionic surfactants
efavirenz
flaxseed oil
nanostructured lipid carriers
nanocarrier
docohexaenoic acid
neuroprotection
neuroinflammation
fluconazole
Box‒Behnken design
nanotransfersome
ulcer index
zone of inhibition
rheological behavior
ex vivo permeation
nanomedicine
cancer
doxorubicin
melanoma
drug delivery
ultrasound contrast agents
phospholipid coating
ligand distribution
cholesterol
acoustic response
microbubble
lipid phase
dialysis
ammonia
intoxication
cyanocobalamin
vitamin B12
atopic dermatitis
psoriasis
transferosomes
lipid vesicles
skin topical delivery
oligonucleotide
self-emulsifying drug delivery systems
hydrophobic ion pairing
intestinal permeation enhancers
Caco-2 monolayer
clarithromycin
solid lipid nanoparticles
optimization
permeation
pharmacokinetics
follicular targeting
dexamethasone
alopecia areata
lipomers
lipid polymer hybrid nanocapsules
biodistribution
skin
ethyl cellulose
n/a
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