Non-small Cell Lung Cancer: Current Therapies and New Targeted Treatments

Non-small Cell Lung Cancer: Current Therapies and New Targeted Treatments

Conventional lung cancer treatments were once limited to surgery, radiation, and chemotherapy. However, gefitinib, a targeted drug, was launched in 2004, and the situation changed. Cancer cases that were highly responsive to gefitinib were later discovered to have epithelial growth factor receptor (...

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Bibliografski detalji
Daljnji autori: Uchino, Junji (Urednik)
Format: Poglavlje knjige
Izdano: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Teme:
Medicine
non-small cell lung cancer
previously treated patients
phase I/II trial
chemotherapy
docetaxel
S-1
immunotherapy
rechallenge
retrospective analysis
pulmonary pleomorphic carcinoma
prognostic factor
glucose transporter 1
lung cancer
multiple cancers
metastasis
sequencing
mutation
genomic diagnosis
FDG-PET
immune checkpoint inhibitor
PD-1
prognosis
RAD51B methylation
PD-L1 expression
predictive biomarker
PD-1 blockade
interstitial lung disease
pulmonary fibrosis
radiology and other imaging
non-small-cell lung cancer
epidermal growth factor receptor
tyrosine kinase inhibitors
TP53 mutations
responsiveness
targeted therapy
network meta-analysis
stage IIIA-N2
surgery
immune checkpoint inhibitors
biomarker
nonsmall cell lung cancer
HIP1R
PD-L1
RUNX1
methylation
survival
EGFR-TKI
T790M
osimertinib
immune-related adverse events
endocrine disorders
tumor-bearing patients
PD-1 inhibitors
PD-L1 inhibitors
meta-analysis
nivolumab
Expanded Access Program
real-world data
daily practice
prognostic factors
NSCLC
KRAS
DNA polymerase beta
platinum-based first-line
adjuvant chemotherapy
β-catenin
lung neoplasms
nucleotide-diphosphate kinase
recurrence
unresectable
salvage surgery
oligometastasis
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