Integrative Multi-Omics in Biomedical Research

Integrative Multi-Omics in Biomedical Research

Genomics technologies revolutionised biomedicine research, but the genome alone is not sufficient to capture biological complexity. Postgenomic methods, typically based on mass spectrometry, comprise the analysis of metabolites, lipids, and proteins and are an essential complement to genomics and tr...

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Altres autors: Gerner, Christopher (Editor), Hill, Michelle (Editor)
Format: Capítol de llibre
Publicat: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Matèries:
Research & information: general
Biology, life sciences
target identification
target validation
label-free method for drugs
anti-angiogenesis
mechanism of action
receptor tyrosine kinases
curcumin
natural products
lipid
lipidomics
cardiac metaplasia
Barrett's esophagus
esophageal adenocarcinoma
microbiota
DNA sensing
IFI16
cGAS
innate immunity
protein interactions
virus-host interactions
post-translational modifications
mass spectrometry
proteomics
transcriptomics
multi-omics
multi-omics analysis
study design
bioinformatics
machine learning
analysis flow
metabolomics
planned myocardial infarction (PMI)
myocardial infarction (MI)
exercise
heart
cheminformatics
batch variations
eicosanoids
fetal calf serum
peroxisomes
host-pathogen interactions
secretome
macrophages
acute myeloid leukemia
HL-60 cell line
ATRA
induced differentiation
transcriptome
proteome
transcription factors
key molecules
regulatory pathway modelling
SRM
endometriosis
inflammation
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