A Changing Perspective for Treatment of Chronic Kidney Disease
Chronic kidney disease (CKD) has become an enormous worldwide health problem, both in developed and less developed countries. The incidence and prevalence of CKD is high, and is associated with increased mortality and morbidity. Of note, CKD is the 12th most common primary cause of death, accountin...
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| स्वरूप: | पुस्तक अध्याय |
| प्रकाशित: |
Basel
MDPI - Multidisciplinary Digital Publishing Institute
2022
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| विषय: | |
| ऑनलाइन पहुंच: | Get Fullteks DOAB: description of the publication |
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| 001 | doab_20_500_12854_78740 | ||
| 005 | 20220224 | ||
| 020 | |a books978-3-0365-2795-6 | ||
| 020 | |a 9783036527956 | ||
| 020 | |a 9783036527949 | ||
| 024 | 7 | |a 10.3390/books978-3-0365-2795-6 |c doi | |
| 041 | 0 | |a English | |
| 042 | |a dc | ||
| 072 | 7 | |a TBX |2 bicssc | |
| 100 | 1 | |a Garibotto, Giacomo |4 edt | |
| 700 | 1 | |a Garibotto, Giacomo |4 oth | |
| 245 | 1 | 0 | |a A Changing Perspective for Treatment of Chronic Kidney Disease |
| 260 | |a Basel |b MDPI - Multidisciplinary Digital Publishing Institute |c 2022 | ||
| 300 | |a 1 electronic resource (158 p.) | ||
| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a Chronic kidney disease (CKD) has become an enormous worldwide health problem, both in developed and less developed countries. The incidence and prevalence of CKD is high, and is associated with increased mortality and morbidity. Of note, CKD is the 12th most common primary cause of death, accounting for about 1 million deaths per year worldwide. CKD and end-stage renal disease are characterized by the progressive development of a series of complications, such as anemia, hyperkalemia, hypervolemia, mineral and bone disorders (CKD-MBD), metabolic acidosis, hyperuricemia and wasting; all of these complications have been shown to be associated with adverse outcomes, and can contribute either individually or in association to the cardiovascular morbidity and mortality observed in CKD. While at this time CKD progression is not treated with high efficacy, new biomarkers of kidney fibrosis have become available in recent years and new treatments for kidney fibrosis and cell loss could become soon available. In addition recent progress in our understanding of CKD pathophysiology together with the development of novel therapeutic agents has led to a renewed attention on the treatment of CKD-associated metabolic complications which are now are amenable to therapeutic interventions. All these important issues are addressed in this volume. | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by/4.0/ |2 cc |4 https://creativecommons.org/licenses/by/4.0/ | ||
| 546 | |a English | ||
| 650 | 7 | |a History of engineering & technology |2 bicssc | |
| 653 | |a heatmap | ||
| 653 | |a clustering | ||
| 653 | |a multivariate statistical analysis | ||
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| 653 | |a risk factors | ||
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| 653 | |a radical nephrectomy | ||
| 653 | |a functional change ratio | ||
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| 653 | |a GLP-1 | ||
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| 653 | |a left ventricular hypertrophy | ||
| 653 | |a left ventricular mass index | ||
| 653 | |a hemodialysis | ||
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| 653 | |a hyperphosphatemia | ||
| 653 | |a cardiovascular disease | ||
| 653 | |a endothelial cells | ||
| 653 | |a procoagulant MVs | ||
| 653 | |a multidimensional prognostic index | ||
| 653 | |a peritoneal dialysis | ||
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| 653 | |a hyperuricemia | ||
| 653 | |a urate lowering treatment | ||
| 653 | |a MANBA | ||
| 653 | |a variants | ||
| 653 | |a estimated glomerular filtration rate (eGFR) | ||
| 653 | |a expression quantitative trait loci (eQTL) | ||
| 653 | |a CKD-MBD | ||
| 856 | 4 | 0 | |a www.oapen.org |u https://mdpi.com/books/pdfview/book/4831 |7 0 |z Get Fullteks |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/78740 |7 0 |z DOAB: description of the publication |