Pharmacogenetics to Avoid Adverse Drug Reactions

Adverse drug reactions are one of the major constraints when using drugs. These adverse reactions can impact healthcare systems as strongly as many prevalent diseases. Identifying DNA variants associated with adverse drug reactions can help personalize medicine and sustain healthcare systems. This b...

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Detalhes bibliográficos
Outros Autores:	López-Fernández, Luis A. (Editor)
Formato:	Capítulo de Livro
Publicado em:	Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Assuntos:	Medicine 5-fluorouracil capecitabine fluoropyrimidine thymidylate synthase thymidylate synthase enhancer region upstream stimulatory factor 1 adverse drug reactions pharmacogenomics epistasis random forest statin cardiovascular disease colorectal cancer personalised medicine toxicity (es)citalopram drug-gene-interaction drug-drug-interaction drug-drug-gene-interaction the PharmLines initiative antipsychotic agents pharmacogenetics cytochrome P-450 enzyme system psychotic disorders precision medicine direct oral anticoagulants clinical implementation atorvastatin SLCO1B1 HLA cutaneous adverse drug reaction SCAR genetic polymorphism antiepileptics CYP450 enzymes platelet reactivity single-nucleotide variants acute coronary syndrome clopidogrel genotype allele polymorphism HLA B CYP2C9*3 cutaneous adverse drug reactions (CADRs) anti-epileptic drugs (AEDS) phenytoin (PHT) genetic risk factors South India India cardiology adverse events guidelines n/a
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Pharmacogenetics to Avoid Adverse Drug Reactions

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